[HTML][HTML] Maternal immune activation in rodent models: A systematic review of neurodevelopmental changes in gene expression and epigenetic modulation in the …

RM Woods, JM Lorusso, HG Potter, JC Neill… - Neuroscience & …, 2021 - Elsevier
Maternal immune activation (mIA) during pregnancy is hypothesised to disrupt offspring
neurodevelopment and predispose offspring to neurodevelopmental disorders such as …

A role for somatostatin-positive interneurons in neuro-oscillatory and information processing deficits in schizophrenia

AB Van Derveer, G Bastos, AD Ferrell… - Schizophrenia …, 2021 - academic.oup.com
Alterations in neocortical GABAergic interneurons (INs) have been affiliated with
neuropsychiatric diseases, including schizophrenia (SZ). Significant progress has been …

The nature of prefrontal cortical GABA neuron alterations in schizophrenia: markedly lower somatostatin and parvalbumin gene expression without missing neurons

SJ Dienel, KN Fish, DA Lewis - American Journal of …, 2023 - Am Psychiatric Assoc
Objective: In schizophrenia, somatostatin (SST) and parvalbumin (PV) mRNA levels are
lower in the dorsolateral prefrontal cortex (DLPFC), but it remains unclear whether these …

The impact of maternal immune activation on GABAergic interneuron development: A systematic review of rodent studies and their translational implications

B Gillespie, S Panthi, S Sundram, RA Hill - Neuroscience & Biobehavioral …, 2023 - Elsevier
Mothers exposed to infections during pregnancy disproportionally birth children who
develop autism and schizophrenia, disorders associated with altered GABAergic function …

The impact of trophic and immunomodulatory factors on oligodendrocyte maturation: Potential treatments for encephalopathy of prematurity

JEG Vaes, MJV Brandt, N Wanders, MJNL Benders… - Glia, 2021 - Wiley Online Library
Encephalopathy of prematurity (EoP) is a major cause of morbidity in preterm neonates,
causing neurodevelopmental adversities that can lead to lifelong impairments. Preterm birth …

[HTML][HTML] An integrative analysis of identified schizophrenia-associated brain cell types and gene expression changes

W Cai, W Song, Z Liu, DT Maharjan, J Liang… - International journal of …, 2022 - mdpi.com
Schizophrenia (SCZ) is a severe mental disorder that may result in hallucinations, delusions,
and extremely disordered thinking. How each cell type in the brain contributes to SCZ …

[HTML][HTML] Regenerative therapies to restore interneuron disturbances in experimental models of encephalopathy of prematurity

JEG Vaes, CM Kosmeijer, M Kaal, R van Vliet… - International journal of …, 2020 - mdpi.com
Encephalopathy of Prematurity (EoP) is a major cause of morbidity in (extreme) preterm
neonates. Though the majority of EoP research has focused on failure of oligodendrocyte …

The effect of 17β-estradiol on maternal immune activation-induced changes in prepulse inhibition and dopamine receptor and transporter binding in female rats

A Sbisa, S Kusljic, D Zethoven, M van den Buuse… - Schizophrenia …, 2020 - Elsevier
Maternal immune activation (MIA) during pregnancy is associated with an increased risk of
development of schizophrenia in later life. 17β-estradiol treatment may improve …

[HTML][HTML] Timed fetal inflammation and postnatal hypoxia cause cortical white matter injury, interneuron imbalances, and behavioral deficits in a double-hit rat model of …

MJV Brandt, CM Kosmeijer, EJM Achterberg… - Brain, Behavior, & …, 2024 - Elsevier
Extreme preterm birth-associated adversities are a major risk factor for aberrant brain
development, known as encephalopathy of prematurity (EoP), which can lead to long-term …

Somatostatin Neurons in Prefrontal Cortical Microcircuits in Schizophrenia

S Dienel - 2023 - d-scholarship.pitt.edu
Certain cognitive functions, including working memory, are impaired in individuals with
schizophrenia. These cognitive impairments are key predictors of functional outcomes in this …