The C‐type lectin‐like domain superfamily

AN Zelensky, JE Gready - The FEBS journal, 2005 - Wiley Online Library
The superfamily of proteins containing C‐type lectin‐like domains (CTLDs) is a large group
of extracellular Metazoan proteins with diverse functions. The CTLD structure has a …

Biological determinants of radioresistance and their remediation in pancreatic cancer

P Seshacharyulu, MJ Baine, JJ Souchek… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Despite recent advances in radiotherapy, a majority of patients diagnosed with pancreatic
cancer (PC) do not achieve objective responses due to the existence of intrinsic and …

Identification of a three-biomarker panel in urine for early detection of pancreatic adenocarcinoma

TP Radon, NJ Massat, R Jones, W Alrawashdeh… - Clinical Cancer …, 2015 - AACR
Purpose: Noninvasive biomarkers for early detection of pancreatic ductal adenocarcinoma
(PDAC) are currently not available. Here, we aimed to identify a set of urine proteins able to …

A combination of urinary biomarker panel and PancRISK score for earlier detection of pancreatic cancer: A case–control study

S Debernardi, H O'Brien, AS Algahmdi, N Malats… - PLoS …, 2020 - journals.plos.org
Background Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with
around 9% of patients surviving> 5 years. Asymptomatic in its initial stages, PDAC is mostly …

[HTML][HTML] Vitamin B12 regulates the transcriptional, metabolic, and epigenetic programing in human ileal epithelial cells

Y Ge, M Zadeh, M Mohamadzadeh - Nutrients, 2022 - mdpi.com
Vitamin B12 (VB12) is a micronutrient that is essential for DNA synthesis and cellular energy
production. We recently demonstrated that VB12 oral supplementation coordinates ileal …

Bifidobacterium longum supplementation improved high-fat-fed-induced metabolic syndrome and promoted intestinal Reg I gene expression

JJ Chen, R Wang, X Li, R Wang - Experimental Biology and …, 2011 - journals.sagepub.com
Recent evidence suggests that intestinal Bifidobacterium species (spp.) positively correlates
with improved insulin resistance and obesity, and this might be linked to metabolic …

Recognition of microbial glycans by soluble human lectins

DA Wesener, A Dugan, LL Kiessling - Current opinion in structural biology, 2017 - Elsevier
Highlights•Elucidating lectin selectivity for microbial glycans could yield new antibiotic
strategies.•Microbe-binding lectins can bind an unexpectedly wide range of glycan …

REG3A accelerates pancreatic cancer cell growth under IL-6-associated inflammatory condition: Involvement of a REG3A–JAK2/STAT3 positive feedback loop

X Liu, J Wang, H Wang, G Yin, Y Liu, X Lei, M Xiang - Cancer letters, 2015 - Elsevier
Regenerating gene protein (REG) 3A is a 19 kD secretory pancreas protein with pro-growth
function. Previously we demonstrated that overexpression of REG3A, acting as a key …

[图书][B] Animal lectins: form, function and clinical applications

GS Gupta - 2012 - books.google.com
Animal Lectins: Form, Function and Clinical Applications presents up-to-date knowledge of
animal lectins. Detailed descriptions on biological activities, tissue and/or subcellular …

mRNAs and protein synthetic machinery localize into regenerating spinal cord axons when they are provided a substrate that supports growth

AL Kalinski, R Sachdeva, C Gomes, SJ Lee… - Journal of …, 2015 - Soc Neuroscience
Although intra-axonal protein synthesis is well recognized in cultured neurons and during
development in vivo, there have been few reports of mRNA localization and/or intra-axonal …