Functional carbon quantum dots for ocular imaging and therapeutic applications

VB Kumar, I Sher, S Rencus‐Lazar, Y Rotenstreich… - Small, 2023 - Wiley Online Library
Carbon quantum dots (CDs) are a class of emerging carbonaceous nanomaterials that have
received considerable attention due to their excellent fluorescent properties, extremely small …

Nanomedicine for the detection and treatment of ocular bacterial infections

X Huang, L Li, Z Chen, H Yu, X You, N Kong… - Advanced …, 2023 - Wiley Online Library
Ocular bacterial infection is a prevalent cause of blindness worldwide, with substantial
consequences for normal human life. Traditional treatments for ocular bacterial infections …

NLRP3 selectively drives IL-1β secretion by Pseudomonas aeruginosa infected neutrophils and regulates corneal disease severity

MS Minns, K Liboro, TS Lima, S Abbondante… - Nature …, 2023 - nature.com
Macrophages infected with Gram-negative bacteria expressing Type III secretion system
(T3SS) activate the NLRC4 inflammasome, resulting in Gasdermin D (GSDMD)-dependent …

Multienzyme‐Like Nanozyme Encapsulated Ocular Microneedles for Keratitis Treatment

S Liu, Q Bai, Y Jiang, Y Gao, Z Chen, L Shang… - Small, 2024 - Wiley Online Library
Keratitis, an inflammation of the cornea caused by bacterial or fungal infections, is one of the
leading causes of severe visual disability and blindness. Keratitis treatment requires both …

[HTML][HTML] Antimicrobial peptides loaded collagen nanosheets with enhanced antibacterial activity, corneal wound healing and M1 macrophage polarization in bacterial …

H Huang, Y Xie, J Zhong, Z Fu, P Wu, X Chen… - Composites Part B …, 2024 - Elsevier
Bacterial keratitis is one of the leading causes of blindness in the world. Frequent
administration of antibiotic eye drops is the first-line treatment, which has difficulties in …

Tetraspanin CD9-derived peptides inhibit Pseudomonas aeruginosa corneal infection and aid in wound healing of corneal epithelial cells

PK Jadi, A Dave, R Issa, K Tabbasum, K Okurowska… - The Ocular Surface, 2024 - Elsevier
Pseudomonas aeruginosa is a leading cause of corneal infection both within India and
globally, often causing a loss of vision. Increasing antimicrobial resistance among the …

Candida Biofilm Eye Infection: Main Aspects and Advance in Novel Agents as Potential Source of Treatment

F Petrillo, M Sinoca, AM Fea, M Galdiero, A Maione… - Antibiotics, 2023 - mdpi.com
Fungi represent a very important cause of microbial eye infections, especially in tropical and
developing countries, as they could cause sight-threating disease, such as keratitis and …

A clearer vision: a mini-review on contact lenses

LM Shaker, AA Al-Amiery, WK Al-Azzawi - Journal of Optics, 2024 - Springer
Contact lenses have become increasingly popular over the years due to their convenience
and improved visual acuity compared to eyeglasses. This mini-review explores the different …

Ciprofloxacin resistance and tolerance of Pseudomonas aeruginosa ocular isolates

M Khan, K Ma, I Wan, MDP Willcox - Contact Lens and Anterior Eye, 2023 - Elsevier
Purpose Tolerance to antibiotics may occur due to changes in bacterial growth patterns and
can be a precursor to development of resistance. However, there is a lack of information on …

A facile method to construct ZIF-8 MOFs on contact lens for high antibiotics loading and self-defensive release

Y Shao, H Suo, S Wang, Y Peng, X Chu, Z Long… - Chemical Engineering …, 2024 - Elsevier
Eye trauma, ophthalmic surgery and contact lens (CL) wearing cause corneal infection and
bacterial biofilms formation, which further lead to corneal ulcer and perforation. In view of the …