Canine reproductive physiology exhibits several unusual features. Among the most
interesting of these are the lack of an acute luteolytic mechanism, coinciding with the …

Endometrial receptivity and embryo implantation processes are a major point of pregnancy
failure in many mammalian species, including humans. Although reproductive biology in …

Glucocorticoids modulate the feto-maternal interface during the induction of parturition. In
the dog, the prepartum rise of cortisol in the maternal circulation appears to be erratic, and …

Prolactin (PRL) is a polypeptide hormone with a wide range of physiological functions, and
is critical for female reproduction. PRL exerts its action by binding to membrane bound …

Canine pregnancy relies on luteal steroidogenesis for progesterone (P4) production. The
canine placenta responds to P4, depending on the nuclear P4 receptor (PGR). This has …

Inhibins are gonadal glycoprotein hormones whose main endocrine function is to inhibit
pituitary FSH secretion. In addition to testes and ovaries, other steroid-producing organs are …

Among domestic animal species, the reproductive biology of the dog belongs to the most
peculiar. This includes the conceptus-maternal communication and endocrine mechanisms …

The fate of the canine corpus luteum (CL) differs from that of other domestic species: beyond
the extended luteal regression observed in both pregnant and non-pregnant cycles, active …

In the domestic dog, placentation arises from central implantation, passing through a
transitional, yet important stage of choriovitelline placenta (yolk sac placenta), on the way to …

The cellular mechanisms underlying normal and pathological endometrial bleeding are not
well understood, although abnormalities in the structure of endometrial blood vessels may …