Background Cultured meat has emerged as a breakthrough technology for the global food
industry, which was considered as a potential solution to mitigate serious environmental …

Single-use technologies have transformed conventional biopharmaceutical manufacturing,
and their adoption is increasing rapidly for emerging applications like antibody–drug …

With an increasing demand for efficacious, safe, and affordable vaccines for human and
animal use, process intensification in cell culture-based viral vaccine production demands …

Chinese hamster ovary (CHO) cells in culture are known to consume large amounts of
nutrients and divert most of them toward byproducts, some of which, including lactate and …

In this study, we demonstrated the first, to our knowledge, integrated continuous bioprocess
(ICB) designed for the production of acid‐sensitive monoclonal antibodies, prone to …

Much of the biopharmaceutical industry's success over the past 30 years has relied on
products derived from Chinese Hamster Ovary (CHO) cell lines. During this time …

One of the main challenges in the development of bioprocesses based on cell transient
expression is the commonly reported reduction of cell specific productivity at increasing cell …

Manufacturing process of biopharmaceuticals usually starts from culturing recombinant
protein producing cells, predominately Chinese Hamster Ovary (CHO) cells, in bioreactors …

The high population growth rate, massive animal food consumption, fast economic progress,
and limited food resources could lead to a food crisis in the future. There is a huge …

Universal red blood cells (RBCs) differentiated from O-negative human induced pluripotent
stem cells (hiPSCs) could find applications in transfusion medicine. Given that each …