Polysaccharides are the most abundant naturally available carbohydrate polymers;
composed of monosaccharide units covalently connected together. Chitosan is the most …

The emerging field of precision medicine is rapidly growing, fostered by the advances in
genome mapping and molecular diagnosis. In general, the translation of these advances …

Protein corona significantly affects in vivo fate of nanoparticles including biodistribution and
half-life. Without manipulating the physicochemical properties of nanoparticles with …

Colon-targeted drug delivery systems is an active area of research that is designed to
selectively release the drug in the colonic environment to enhance the oral delivery of active …

Thiolated polymers designated “thiomers” are obtained by covalent attachment of thiol
functionalities on the polymeric backbone of polymers. In 1998 these polymers were first …

The use of peptides and proteins in the pharmaceutical field has increased dramatically over
recent years. They have been especially relevant to advances in the treatment of cancer …

Over the last 30 years, genetically engineered DNA has been tested as novel vaccination
strategy against various diseases, including human immunodeficiency virus (HIV), hepatitis …

Gene therapy is a novel approach for cancer treatment and investigation for suitable gene
delivery systems is remarkable. Here, preparation of a polyelectrolyte complex containing …

Chitosan has emerged as a promising polysaccharide for gene/siRNA delivery. However,
additional works will be required to modify chitosan nanoparticles. In the present study …

Breast cancer is the most prevalent type of cancer in women; hence, many researches have
been focused on developing effective treatment protocols. In this study, a novel nanocarrier …