Lessons from the genomes of lindane‐degrading sphingomonads

Y Nagata, H Kato, Y Ohtsubo… - Environmental …, 2019 - Wiley Online Library
Bacterial strains capable of degrading man‐made xenobiotic compounds are good
materials to study bacterial evolution towards new metabolic functions. Lindane (γ …

Comparative genomic analysis of nine Sphingobium strains: insights into their evolution and hexachlorocyclohexane (HCH) degradation pathways

H Verma, R Kumar, P Oldach, N Sangwan, JP Khurana… - BMC genomics, 2014 - Springer
Background Sphingobium spp. are efficient degraders of a wide range of chlorinated and
aromatic hydrocarbons. In particular, strains which harbour the lin pathway genes mediating …

Enantiomer and Carbon Isotope Fractionation of α-Hexachlorocyclohexane by Sphingobium indicum Strain B90A and the Corresponding Enzymes

Y Liu, L Wu, P Kohli, R Kumar… - Environmental …, 2019 - ACS Publications
Chiral organic contaminants, like α-hexachlorocyclohexane (α-HCH), showed isotope
fractionation and enantiomer fractionation during biodegradation. This study aims to …

Biodegradation of organochlorine pesticides

Y Nagata, M Tabata, Y Ohtsubo… - Manual of environmental …, 2016 - Wiley Online Library
The widespread use of organochlorine pesticides (OCPs), mainly in the past, has caused
serious environmental problems. Many OCPs were recently categorized as persistent …

Assessing aerobic biotransformation of hexachlorocyclohexane isomers by compound-specific isotope analysis

IE Schilling, CE Bopp, R Lal, HPE Kohler… - … science & technology, 2019 - ACS Publications
Contamination of soils and sediments with the highly persistent hexachlorocyclohexanes
(HCHs) continues to be a threat for humans and the environment. Despite the existence of …

Metabolomics of hexachlorocyclohexane (HCH) transformation: ratio of LinA to LinB determines metabolic fate of HCH isomers

B Geueke, N Garg, S Ghosh… - Environmental …, 2013 - Wiley Online Library
Although the production and use of technical hexachlorocyclohexane (HCH) and lindane
(the purified insecticidal isomer γ‐HCH) are prohibited in most countries, residual …

Genomic Analysis of γ-Hexachlorocyclohexane-Degrading Sphingopyxis lindanitolerans WS5A3p Strain in the Context of the Pangenome of Sphingopyxis

MA Kaminski, A Sobczak, A Dziembowski, L Lipinski - Genes, 2019 - mdpi.com
Sphingopyxis inhabit diverse environmental niches, including marine, freshwater, oceans,
soil and anthropogenic sites. The genus includes 20 phylogenetically distinct, valid species …

Insights into ongoing evolution of the hexachlorocyclohexane catabolic pathway from comparative genomics of ten Sphingomonadaceae strains

SL Pearce, JG Oakeshott… - G3: Genes, Genomes …, 2015 - academic.oup.com
Hexachlorocyclohexane (HCH), a synthetic organochloride, was first used as a broad-acre
insecticide in the 1940s, and many HCH-degrading bacterial strains have been isolated …

Functional screening of enzymes and bacteria for the dechlorination of hexachlorocyclohexane by a high-throughput colorimetric assay

P Sharma, S Jindal, K Bala, K Kumari, N Niharika… - Biodegradation, 2014 - Springer
Two distinct microbial dehalogenases are involved in the first steps of degradation of
hexachlorocyclohexane (HCH) isomers. The enzymes, LinA and LinB, catalyze …

Enantioselective dehydrochlorination of δ-hexachlorocyclohexane and δ-pentachlorocyclohexene by LinA1 and LinA2 from Sphingobium indicum B90A

B Geueke, ME Miska, T Poiger, D Rentsch… - Applied and …, 2013 - Am Soc Microbiol
ABSTRACT δ-Hexachlorocyclohexane (δ-HCH), one of the prevalent isomers of technical
HCH, was enantioselectively dehydrochlorinated by the dehydrochlorinases LinA1 and …