Spinal cord injury remains a scientific and therapeutic challenge with great cost to
individuals and society. The goal of research in this field is to find a means of restoring lost …

The central nervous system is not a static, hard-wired organ. Examples of neuroplasticity,
whether at the level of the synapse, the cell, or within and between circuits, can be found …

Neural progenitor cell (NPC) transplantation has high therapeutic potential in neurological
disorders. Functional restoration may depend on the formation of reciprocal connections …

Several neurotrophic factors have been identified that influence neuronal populations during
central nervous system development, maturation, and senescence. To examine the …

Three neuroanatomical tracers have been employed to map the axonal projections formed
between transplants of fetal spinal cord tissue and the surrounding host spinal cord in adult …

There is growing interest in the use of neural precursor cells to treat spinal cord injury (SCI).
Despite extensive pre-clinical research, it remains unclear as to which donor neuron …

Despite advancement of neural progenitor cell transplantation to spinal cord injury clinical
trials, there remains a lack of understanding of how biological sex of transplanted cells …

Spinal cord injury (SCI) disrupts the long axonal tracts of the spinal cord leading to
devastating loss of function. Cell transplantation in the injured spinal cord has the potential …

Abstract SPINAL CORD INJURY (SCI) continues to be an insidious and challenging
problem for scientists and clinicians. Recent neuroscientific advances have changed the …

This article reviews recent findings concerning the feasibility, basic neurobiology, and
potential functional benefits of fetal CNS tissue grafts into acute and chronic lesions of the …