Diffuse midline gliomas (DMG) are a highly aggressive and universally fatal subgroup of
pediatric tumors responsible for the majority of childhood brain tumor deaths. Median overall …

Diffuse midline glioma (DMG) is a heterogeneous group of aggressive pediatric brain tumors
with a fatal prognosis. The biological hallmark in the major part of the cases is H3K27 …

Brain tumors are among the most dangerous diseases that lead to mortality after a period of
time from injury. Therefore, physicians and healthcare professionals are advised to make an …

Background Central nervous system tumor (CNST) is one of the most complicated and lethal
forms of human tumors with very limited treatment options. In recent years, growing evidence …

Glioblastoma (GBM) tumors are the most aggressive primary brain tumors in adults that,
despite maximum treatment, carry a dismal prognosis. GBM tumors exhibit tissue hypoxia …

Viruses and tumors are two pathologies that negatively impact human health, but what
occurs when a virus encounters a tumor? A global consensus among cancer patients …

Glioblastoma (GBM) represents the most aggressive primary brain tumor, and urgently
requires effective treatments. Oncolytic adenovirus (OA) shows promise as a potential …

Since the discovery that cGAS/STING recognizes endogenous DNA released from dying
cancer cells and induces type I interferon and antitumor T cell responses, efforts to …

Introduction High-grade gliomas (HGG) are the most common malignant primary brain
tumors in adults, with a median survival of~ 18 months. The standard of care (SOC) is …

Abstract Oncolytic adenoviruses (OAds), engineered Ads preferentially infect and lyse tumor
cells, have attracted remarkable attention as immunotherapy weapons for the treatment of …