This paper is the forty-fifth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

Medical research is changing into direction of precision therapy, thus, sophisticated
preclinical models are urgently needed. In human pathogenic virus research, the major …

HIV-associated sensory neuropathies (HIV-SN) are prevalent in> 50% of patients aged over
45 years many of which report moderate to severe chronic pain. Previous preclinical studies …

Despite advances in the treatment of human immunodeficiency virus (HIV), approximately
one-half of people infected with HIV (PWH) experience neurocognitive impairment. Opioid …

Opioid use disorder (OUD) and HIV are comorbid epidemics that can increase depression.
HIV and the viral protein Tat can directly induce neuronal injury within reward and …

Many persons infected with HIV-1 (PWH) and opioid-dependent individuals experience
deficits in sociability that interfere with daily living. Sociability is regulated by the prefrontal …

Background Human immunodeficiency virus (HIV) affects nearly 40 million people globally,
with roughly 80% of all people living with HIV receiving antiretroviral therapy. Antiretroviral …

Various research studies that have investigated the association between HIV infection and
addiction underpin the role of various drugs of abuse in impairing immunological and non …

The cannabinoid receptor type 1 (CB1R) is a promising therapeutic target for various
neurodegenerative diseases, including HIV-1-associated neurocognitive disorder (HAND) …

Background Since the introduction of combination antiretroviral therapy (cART) the brain has
become an important human immunodeficiency virus (HIV) reservoir due to the relatively low …