Thiadiazole derivatives as anticancer agents

M Szeliga - Pharmacological Reports, 2020 - Springer
In spite of substantial progress made toward understanding cancer pathogenesis, this
disease remains one of the leading causes of mortality. Thus, there is an urgent need to …

[HTML][HTML] Mechanism-based approaches of 1, 3, 4 thiadiazole scaffolds as potent enzyme inhibitors for cytotoxicity and antiviral activity

D Kumar, H Kumar, V Kumar, A Deep, A Sharma… - Medicine in Drug …, 2023 - Elsevier
Significant progress in understanding cancer pathogenesis, it remains one of the leading
causes of death after cardiovascular diseases. Similarly viral infections have emerged from …

Isoindole derivatives: Propitious anticancer structural motifs

R Kaur Bhatia - Current topics in medicinal chemistry, 2017 - ingentaconnect.com
Isoindole derivatives constitute an important class of biologically active heterocyclic
compounds and continue to attract considerable attention due to their diverse …

1, 3, 4-Thiadiazole based anticancer agents

A Aliabadi - Anti-Cancer Agents in Medicinal Chemistry …, 2016 - ingentaconnect.com
In recent years, researchers like medicinal chemists in the field of medicinal chemistry have
widely utilized the 1, 3, 4-thiadiazole nucleus to investigate its biological and …

Human cancer cell line based approach of 1, 3, 4-thiadiazole and its fused ring: a comprehensive review

V Raj, A Rai, S Saha - Anti-Cancer Agents in Medicinal …, 2017 - ingentaconnect.com
The chemistry of heterocyclic containing, 1, 3, 4-thiadiazole has been an interesting field of
study from ancient years. Subsequently, 1, 3, 4-thiadiazole nucleus constitutes a significant …

An Efficient Synthesis of 1-(1,3-Dioxoisoindolin-2-yl)-3-aryl Urea Analogs as Anticancer and Antioxidant Agents: An Insight into Experimental and In Silico Studies

O Afzal, MJ Ahsan - Molecules, 2023 - mdpi.com
The present investigation reports the efficient multistep synthesis of 1-(1, 3-dioxoisoindolin-2-
yl)-3-aryl urea analogs (7a–f) in good yields. All the 1-(1, 3-dioxoisoindolin-2-yl)-3-aryl urea …

Insights into synthesis, reactivity, and biological activity of N-isoindoline-1, 3-diones heterocycles: a systematic literature review

Z Ou-Ichen, A Boussetta, K Ouchetto, A Hafid… - Journal of the Iranian …, 2024 - Springer
This review paper provides a comprehensive overview of recent advancements in the
synthesis, reactivity, and applications of N-isoindoline-1, 3-dione heterocycles. These …

[PDF][PDF] Synthesis and Cytotoxicity Evaluation of N-(5-(Substituted-benzylthio)-1, 3, 4-thiadiazole-2-yl)-2-p-nitrophenylacetamide Derivatives as Potential Anticancer …

A Aliabadi, R Fereidooni, A Kiani - Iranian Journal of Chemistry and …, 2019 - ijcce.ac.ir
Cancer is a big global problem and is one of the top and main causes of mortality in
developed countries. Many of the current treatments and anticancer therapeutics have …

[PDF][PDF] SYNTHESIS, CHARACTERIZATION AND ANTI-PROLIFERATIVE EVALUATION OF ISOINDOLINE-1, 3-DIONE DERIVATIVES

AS Sarthi, S Saraf, J Singh, S Saraf… - Acta Biomed.(94) …, 2023 - mattioli.1885journals.com
In the present study, some potential anti-proliferative compounds: isoindoline-1, 3-dione
derivatives A1-A11 have been synthesized from various Schiff bases (aromatic amines) 1 …

In vitro and in silico biological evaluation of phthalimide derivatives as antiproliferative agents

CA Sierra-Rivera, M Kashif… - … en Ciencias Químico …, 2022 - medigraphic.com
Phthalimide is considered a scaffold for the development of new anticancer agents. In this
work, the antiproliferative activity of forty-three phthalimide derivatives was evaluated …