The interactions of magnesium sulfate and cromoglycate in a rat model of orofacial pain; the role of magnesium on mast cell degranulation in neuroinflammation

D Srebro, B Dožić, S Vučković, K Savić Vujović… - International Journal of …, 2023 - mdpi.com
Mast cell degranulation impacts the development of pain and inflammation during tissue
injury. We investigated the antinociceptive effect of a combination of cromoglycate and …

[HTML][HTML] A comprehensive painkillers screening by assessing zebrafish behaviors after caudal fin amputation

G Audira, JC Huang, KHC Chen, KA Kurnia… - Biomedicine & …, 2023 - Elsevier
Recently, the usage of zebrafish for pain studies has increased in the past years, especially
due to its robust pain-stimulated behaviors. Fin amputation has been demonstrated to …

Synergism between naproxen and rutin in a mouse model of visceral pain

AJ Alonso‐Castro… - Drug Development …, 2017 - Wiley Online Library
ABSTRACT Preclinical Research The aim of the present study was to evaluate the
antinociceptive interaction between naproxen and the glycoside flavonoid, rutin in the acetic …

Isobolographic analysis of the interaction between tapentadol and ketorolac in a mouse model of visceral pain

JR Zapata‐Morales… - Drug Development …, 2016 - Wiley Online Library
Abstract Preclinical Research The aim of this experimental assay was to assess the
antinociceptive interaction between tapentadol and ketorolac in the acetic acid‐induced …

Analgesic activities of the mixed opioid and NPFF receptors agonist DN-9 in a mouse model of formalin-induced orofacial inflammatory pain

T Zhang, W Zhao, M Zhang, B Xu, X Shi, Q Zhang… - Peptides, 2018 - Elsevier
Orofacial pain is one of the most common pain conditions and compromises the quality of
life of the sufferer. Several studies have shown that opioid agonists produced significant …

[PDF][PDF] Nitridergic Modulation of COX-2 Efficacy

H Miranda, V Noriega, F Moreno, F Sierralta… - 2022 - repositorio.udd.cl
Pain is a common unpleasant sensory and emotional experience, in which are frequently
used in their treatment the nonsteroidal anti-inflammatory drugs (NSAIDs). A group of agents …

[PDF][PDF] Isobolographic Antinociception of Nonsteroidal Anti-inflammatory Drugs in Rodent Formalin Orofacial Pain Pharmaceutical and Biomedical Research. 2020; 6 …

V Noriega, F Sierralta, N Aranda, R Sotomayor-Zárate… - 2018 - sid.ir
Background: Diverse studies suggest that non-steroidal anti-inflammatory drugs (NSAIDs)
induce antinociception through the inhibition of cyclooxygenases. Objectives: This study …

Evaluación de la interacción antinociceptiva entre Rutina y Naproxeno utilizando análisis isobolográfico

JER VELAZQUEZ - 2017 - repositorio.ugto.mx
El uso de combinaciones farmacológicas entre analgésicos antiinflamatorios no esteroideos
(AINEs) y opioides puede traer consigo una mayor actividad analgésicay menores efectos …

Isobolographic Antinociception of Nonsteroidal Anti-inflammatory Drugs in Rodent Formalin Orofacial Pain

V Noriega, F Sierralta, N Aranda… - Pharmaceutical and …, 2020 - pbr.mazums.ac.ir
Background: Diverse studies suggest that non-steroidal anti-inflammatory drugs (NSAIDs)
induce antinociception through the inhibition of cyclooxygenases. Objectives: This study …

[PDF][PDF] The analgesic effect of Berchemia berchemiaefolia are mediated via suppression of p38 MAPK activation in rats

GH Lee, KY Hyun - ijiset.com
Aims: We carried out the present study to demonstrate that oral treatment with Berchemia
berchemiaefolia extract (BBE) protects SD rats from pain. Methods: Animal experimental …