[HTML][HTML] Colon cancer: a clinician's perspective in 2019
M Ahmed - Gastroenterology research, 2020 - ncbi.nlm.nih.gov
Colon cancer is a common preventable cancer. With the adoption of widespread colon
cancer screening in the developed countries, the incidence and mortality of colon cancer …
cancer screening in the developed countries, the incidence and mortality of colon cancer …
Pathological features and prognostication in colorectal cancer
The prognostication of colorectal cancer (CRC) has traditionally relied on staging as defined
by the Union for International Cancer Control (UICC) and American Joint Committee on …
by the Union for International Cancer Control (UICC) and American Joint Committee on …
Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRASG12C-Mutant Non–Small Cell Lung Cancer
Purpose: Patients with KRAS-mutant non–small cell lung cancer (NSCLC) with brain
metastases (BM) have a poor prognosis. Adagrasib (MRTX849), a potent oral small …
metastases (BM) have a poor prognosis. Adagrasib (MRTX849), a potent oral small …
[HTML][HTML] The current understanding on the impact of KRAS on colorectal cancer
M Meng, K Zhong, T Jiang, Z Liu, HY Kwan… - Biomedicine & …, 2021 - Elsevier
KRAS (kirsten rat sarcoma viral oncogene) is a member of the RAS family. KRAS mutations
are one of most dominant mutations in colorectal cancer (CRC). The impact of KRAS …
are one of most dominant mutations in colorectal cancer (CRC). The impact of KRAS …
RAS-mediated oncogenic signaling pathways in human malignancies
Abnormally activated RAS proteins are the main oncogenic driver that governs the
functioning of major signaling pathways involved in the initiation and development of human …
functioning of major signaling pathways involved in the initiation and development of human …
[HTML][HTML] Machine learning detects pan-cancer ras pathway activation in the cancer genome atlas
Precision oncology uses genomic evidence to match patients with treatment but often fails to
identify all patients who may respond. The transcriptome of these" hidden responders" may …
identify all patients who may respond. The transcriptome of these" hidden responders" may …
Targeting KRAS in colorectal cancer: a bench to bedside review
Colorectal cancer (CRC) is a heterogeneous disease with a myriad of alterations at the
cellular and molecular levels. Kristen rat sarcoma (KRAS) mutations occur in up to 40% of …
cellular and molecular levels. Kristen rat sarcoma (KRAS) mutations occur in up to 40% of …
Improving diagnosis, prognosis and prediction by using biomarkers in CRC patients
TK Nikolouzakis, L Vassilopoulou… - Oncology …, 2018 - spandidos-publications.com
Colorectal cancer (CRC) is among the most common cancers. In fact, it is placed in the third
place among the most diagnosed cancer in men, after lung and prostate cancer, and in the …
place among the most diagnosed cancer in men, after lung and prostate cancer, and in the …
[PDF][PDF] Research progress on KRAS mutations in colorectal cancer
M Cefalì, S Epistolio… - J. Cancer …, 2021 - pdfs.semanticscholar.org
The RAS gene family, responsible for signal transduction within the mitogen activated
protein kinase (MAPK) and phosphatidylinositol 3 kinase (PI3K) pathways, is frequently …
protein kinase (MAPK) and phosphatidylinositol 3 kinase (PI3K) pathways, is frequently …
Microenvironmental reactive oxygen species in colorectal cancer: involved processes and therapeutic opportunities
Simple Summary Colorectal cancer is a disease associated with a high mortality rate. During
the tumorigenic process, several factors and signaling molecules produced by tumor cells …
the tumorigenic process, several factors and signaling molecules produced by tumor cells …