For many individuals in industrialized nations, the widespread adoption of electric lighting
has dramatically affected the circadian organization of physiology and behavior. Although …

It is commonly accepted that melatonin (N-acetyl-5-methoxytryptamine), the most relevant
pineal secretory product, has oncostatic properties in a wide variety of tumors and …

Lung cancer is becoming increasingly common in women and in the United States accounts
for more female cancer deaths annually than breast cancer. Many epidemiological studies …

In this article, we review the experimental data supporting an oncostatic role of melatonin on
hormone‐dependent mammary tumors. Beginning with the evidence on the role of …

Melatonin is a phylogenetically well-preserved molecule with diverse physiological
functions. In addition to its well-known regulatory control of the sleep/wake cycle, as well as …

This review article discusses recent work on the melatonin‐mediated circadian regulation
and integration of molecular, dietary, and metabolic signaling mechanisms involved in …

An expression construct containing the cDNA encoding a modified aequorea green
fluorescent protein (GFP) ligated to the 5′-end of the rat androgen receptor (AR) cDNA …

The authors have shown that, via activation of its MT1 receptor, melatonin modulates the
transcriptional activity of various nuclear receptors and the proliferation of both ERα+ and …

The growth of rat hepatoma 7288CTC in vivo is stimulated by the uptake of linoleic acid (LA)
and its metabolism to 13-hydroxyoctadecadienoic acid (13-HODE), an important mitogenic …

Melatonin is an indolic hormone produced mainly by the pineal gland. The former
hypothesis of its possible role in mammary cancer development was based on the evidence …