Infectious Diseases Society of America 2024 guidance on the treatment of antimicrobial-resistant gram-negative infections

PD Tamma, EL Heil, JA Justo… - Clinical infectious …, 2024 - academic.oup.com
Abstract Background The Infectious Diseases Society of America (IDSA) is committed to
providing up-to-date guidance on the treatment of antimicrobial-resistant (AMR) infections …

Cefiderocol, a siderophore cephalosporin, as a treatment option for infections caused by carbapenem-resistant Enterobacterales

KS Kaye, T Naas, JM Pogue, GM Rossolini - Infectious Diseases and …, 2023 - Springer
Carbapenem-resistant Enterobacterales (CRE) remain a significant public health threat,
and, despite recent approvals, new antibiotics are needed. Severe infections caused by …

In vitro activity of cefiderocol against MBL-producing Gram-negative bacteria collected in North America and Europe in five consecutive annual multinational SIDERO …

M Takemura, MG Wise, MA Hackel… - Journal of …, 2023 - academic.oup.com
Objectives To evaluate the in vitro antibacterial activity of cefiderocol, a siderophore
cephalosporin against MBL-producing clinical isolates. Methods MBL-producing strains …

An overview of Cefiderocol's therapeutic potential and underlying resistance mechanisms

S Domingues, T Lima, MJ Saavedra, GJ Da Silva - Life, 2023 - mdpi.com
Antimicrobial resistance continues to increase globally and treatment of difficult-to-treat
(DTT) infections, mostly associated with carbapenem-resistant (CR) Pseudomonas …

An NDM-Producing Escherichia coli Clinical Isolate Exhibiting Resistance to Cefiderocol and the Combination of Ceftazidime-Avibactam and Aztreonam: Another …

PJ Simner, Y Bergman, R Conzemius… - Open Forum …, 2023 - academic.oup.com
Background Cefiderocol and ceftazidime-avibactam plus aztreonam (CZA-ATM) are
preferred treatment regimens for New Delhi metallo-β-lactamase (NDM)-producing …

[HTML][HTML] Emergence of Carbapenem-Resistant Uropathogenic Escherichia coli (ST405 and ST167) Strains Carrying blaCTX-M-15, blaNDM-5 and Diverse …

F Mujahid, MH Rasool, M Shafiq, B Aslam, M Khurshid - Pathogens, 2024 - mdpi.com
Background: Urinary tract infections (UTIs) are common infectious diseases in hospital
settings, and they are frequently caused by uropathogenic Escherichia coli (UPEC). The …

Effect of modification of penicillin-binding protein 3 on susceptibility to ceftazidime-avibactam, imipenem-relebactam, meropenem-vaborbactam, aztreonam-avibactam …

C Le Terrier, P Nordmann, C Buchs… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
The impact of penicillin-binding protein 3 (PBP3) modifications that may be identified in
Escherichia coli was evaluated with respect to susceptibility to β-lactam/β-lactamase …

In Vitro Susceptibility of Aztreonam-Vaborbactam, Aztreonam-Relebactam and Aztreonam-Avibactam Associations against Metallo-β-Lactamase-Producing Gram …

C Emeraud, S Bernabeu, L Dortet - Antibiotics, 2023 - mdpi.com
Background: Despite the availability of new options (ceftazidime-avibactam, imipenem-
relebactam, meropenem-vaborbactam and cefiderocol), it is still very difficult to treat …

Evaluation of the MTS™ aztreonam-avibactam strip (Liofilchem) on New Delhi metallo-β-lactamase-producing Enterobacterales

CM Emilie, CM Alice, G Marine, E Farfour… - European Journal of …, 2024 - Springer
The combination of ceftazidime-avibactam (CAZ-AVI) and aztreonam (ATM) is used to treat
MBL-producing Enterobacterales-related infections. The new combination aztreonam …

In Vitro Activities and Inoculum Effects of Cefiderocol and Aztreonam-Avibactam against Metallo-β-Lactamase-Producing Enterobacteriaceae

YS Huang, PY Chen, PC Chou, JT Wang - Microbiology spectrum, 2023 - Am Soc Microbiol
Cefiderocol and aztreonam-avibactam (ATM-AVI) both had activity against carbapenem-
resistant Gram-negative bacilli, including those that produce metallo-β-lactamases (MBLs) …