Cortical granules are membrane bound organelles located in the cortex of unfertilized
oocytes. Following fertilization, cortical granules undergo exocytosis to release their …

Zona pellucida (ZP) is a glycoproteinaceous translucent matrix that surrounds the
mammalian oocyte and plays a critical role in the accomplishment of fertilization. In humans …

Human fertilization begins when spermatozoa bind to the extracellular matrix coating of the
oocyte, known as the zona pellucida (ZP). One spermatozoan then penetrates this matrix …

The mouse zona pellucida is composed of three glycoproteins (ZP1, ZP2, and ZP3), of which
ZP2 is proteolytically cleaved after gamete fusion to prevent polyspermy. This cleavage is …

Human zona pellucida (ZP) matrix is composed of four glycoproteins designated as ZP
glycoprotein-1 (ZP1),-2 (ZP2),-3 (ZP3), and-4 (ZP4). Mutations in the genes encoding human …

Human zona pellucida (ZP) matrix, a delicate network of thin interconnected filaments, is
primarily composed of four glycoproteins, namely, ZP1, ZP2, ZP3, and ZP4. All four zona …

Sperm-zona pellucida (ZP) interaction, involving the binding of sperm surface ligands to
complementary carbohydrates of ZP, is the first direct gamete contact event crucial for …

BACKGROUND: Failures in expression of zona proteins correlate to subfertility in animals.
Low expression of the zona proteins by the growing human oocyte may indicate reduced …

During mammalian fertilisation, the zona pellucida (ZP) matrix surrounding the oocyte is
responsible for the binding of the spermatozoa to the oocyte and induction of the acrosome …

STUDY QUESTION What is the role of carbohydrates in the binding of human sperm to the
zona pellucida (ZP) and what are potential implications for pathogenesis? SUMMARY …