Research progress of therapeutic effects and drug resistance of immunotherapy based on PD-1/PD-L1 blockade

K Pang, ZD Shi, LY Wei, Y Dong, YY Ma, W Wang… - Drug Resistance …, 2023 - Elsevier
The binding of programmed death-1 (PD-1) on the surface of T cells and PD-1 ligand 1 (PD-
L1) on tumor cells can prevent the immune-killing effect of T cells on tumor cells and …

Neoadjuvant therapy in non-small cell lung cancer: basis, promise, and challenges

S Kalvapudi, Y Vedire, S Yendamuri, J Barbi - Frontiers in Oncology, 2023 - frontiersin.org
Introduction Survival rates for early-stage non-small cell lung cancer (NSCLC) remain poor
despite the decade-long established standard of surgical resection and systemic adjuvant …

Predicting pathological response to neoadjuvant or conversion chemoimmunotherapy in stage IB–III non‐small cell lung cancer patients using radiomic features

N Yang, HL Yue, BH Zhang, J Chen, Q Chu… - Thoracic …, 2023 - Wiley Online Library
Background To develop a radiomics model based on chest computed tomography (CT) for
the prediction of a pathological complete response (pCR) after neoadjuvant or conversion …

Efficacy and safety of different cycles of neoadjuvant immunotherapy in resectable non-small cell lung cancer: A systematic review and meta-analysis

L Ye, Y Liu, X Xiang, Z Wang, W Peng, X Wei, S Zhang… - Heliyon, 2024 - cell.com
Background There is no standard consensus on the optimal number of cycles of
neoadjuvant immunotherapy prior to surgery for patients with locoregionally advanced non …

Neoadjuvant therapy with immune checkpoint inhibitors in operable nonsmall cell lung cancer

RM Huber - Current Opinion in Oncology, 2024 - journals.lww.com
Neoadjuvant therapy with immune checkpoint inhibitors in ope... : Current Opinion in Oncology
Neoadjuvant therapy with immune checkpoint inhibitors in operable nonsmall cell lung cancer …

Neoadjuvant nivolumab plus chemotherapy in resectable non‐small‐cell lung cancer in Japanese patients from CheckMate 816

T Mitsudomi, H Ito, M Okada, S Sugawara… - Cancer …, 2024 - Wiley Online Library
In the open‐label, phase III CheckMate 816 study (NCT02998528), neoadjuvant nivolumab
plus chemotherapy demonstrated statistically significant improvements in event‐free survival …

Neoadjuvant cabozantinib restores CD8+ T cells in patients with locally advanced non-metastatic clear cell renal cell carcinoma: A phase 2 trial

MA Bilen, BHT Vo, Y Liu, R Greenwald… - Research …, 2024 - pmc.ncbi.nlm.nih.gov
Cabozantinib is an oral multikinase inhibitor approved for treatment in metastatic renal cell
carcinoma (RCC). We hypothesized that neoadjuvant cabozantinib could downstage …

[HTML][HTML] The Surgical Renaissance: Advancements in Video-Assisted Thoracoscopic Surgery and Robotic-Assisted Thoracic Surgery and Their Impact on Patient …

JM Pan, AA Watkins, CT Stock, SD Moffatt-Bruce… - Cancers, 2024 - mdpi.com
Simple Summary Lung cancer treatment often involves surgical resection. Traditional
resection involves a large thoracotomy incision to access the chest cavity. However …

[HTML][HTML] Immunotherapy for early-stage non-small cell lung cancer: A practical guide of current controversies

WJ Phillips, A Jackson, B Kidane, G Lim, V Navani… - Clinical Lung Cancer, 2025 - Elsevier
The role of immunotherapy as systemic therapy for non-metastatic non-small cell lung
cancer (NSCLC) has evolved rapidly over the last decade. There are several well-conducted …

Molecular Markers, Immune Therapy, and Non-Small Cell Lung Cancer—State-of-the-Art Review for Surgeons

RWC Young, GR Rodriguez, J Kucera… - … & Advanced Surgical …, 2024 - liebertpub.com
Background: Lung cancer is a leading cause of cancer deaths in the United States. An
increasing understanding of relevant non-small cell lung cancer (NSCLC) biomarkers has …