OBJECTIVE: Ascending thoracic aortic aneurysms (ATAA) are a life-threatening condition
due to the risk of rupture or dissection. This risk is increased in the presence of a bicuspid …

The biomechanical adaptation of the arterial wall to hypertension has been studied
extensively in recent years; however, the exact biomechanical contribution of vascular …

We studied the changes in vascular smooth muscle (VSM) cell tone during the adaptation of
rat common carotids to induced hypertension. Hypertension was induced in 8 week old male …

Loss of large artery compliance is an emerging novel predictor of cardiovascular mortality.
Hypoxia-induced pulmonary hypertension (HPH) has been shown to decrease extralobar …

Living tissues can remarkably adapt to their mechanical and biochemical environments
through growth and remodelling mechanisms. Over the years, extensive research has been …

When grafted into an arterial environment in vivo, veins remodel in response to the new
mechanical environment, thereby changing their mechanical properties and potentially …

The inner diameter and wall thickness of rat middle cerebral arteries (MCAs) were measured
in vitro in both a pressure-induced, myogenically-active state and a drug-induced, passive …

Objective This study was performed to determine the feasibility of measuring the elastic
properties of the arterial wall in vivo. To prove this concept, elastic parameters were …

Most arterial mechanics studies have focused on excised non-coronary vessels, with few
studies validating the application of ex-vivo results to in-vivo conditions. A method was …

It is known that hypertension is associated with endothelial dysfunction and that Angiotensin
II (Ang II) is a key player in the pathogenesis of hypertension. We aimed to elucidate whether …