Effect of dexmedetomidine on liver transplantation: a meta-analysis

D Jia, S Guo, X Wu, M Zhao, J Luo, M Cheng… - Frontiers in …, 2023 - frontiersin.org
Background: Dexmedetomidine (DEX), an adjuvant anesthetic, may improve the clinical
outcomes of liver transplantation (LT). Methods: We summarized the relevant clinical trials of …

Mapping theme trends and research frontiers in dexmedetomidine over past decade: a bibliometric analysis

Z Chen, Z Zuo, X Song, Y Zuo, L Zhang… - Drug Design …, 2024 - Taylor & Francis
Background Dexmedetomidine, an α2-adrenergic receptor (α2-AR) agonist, is extensively
used in clinical and animal studies owing to its sedative, analgesic, and anxiolytic effects …

[HTML][HTML] Effects of dexmedetomidine on inflammation and pulmonary function after thoracoscopic surgery for lung cancer: a systematic review and meta-analysis

Y Xu, Y Zhou, JD Maloney, G Shan - Journal of Thoracic Disease, 2023 - ncbi.nlm.nih.gov
Background Surgical resection is the most effective treatment for lung cancer, but it can also
lead to adverse stress reactions in the body. The minimization of lung function damage …

Dexmedetomidine Regulates Macrophage Phenotype Remodeling Through AMPK/SIRT1 to Alleviate Inflammatory Mediators and Lung Injury

Y Zhao, Y Shi, K Li, B Ma, S Lin… - Journal of Biochemical …, 2025 - Wiley Online Library
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is associated with high
morbidity and mortality in the intensive care unit (ICU) and can cause excessive …

The Effect of Dexmedetomidine and Levobupivacaine in an Experimental Ischemia Reperfusion Model

TH Ibrahim, K Sevgi, O Sibel, CA Surhan, K Kaan… - in vivo, 2024 - iv.iiarjournals.org
Background/Aim: Although it has been reported that different molecules are effective in
preventing ischemia-reperfusion (I/R) injury, the most effective treatment is still unknown …

[PDF][PDF] Exploring the impact of dexmedetomidine on short-term outcomes in critically ill sepsis-associated encephalopathy patients.

J Tang, ZG Zhong, CD Wu - European Review for Medical & …, 2024 - europeanreview.org
OBJECTIVE: Dexmedetomidine has demonstrated potential in preclinical medical research
as a protective agent against inflammatory injuries and a provider of neuroprotective …

[PDF][PDF] Dexmedetomidine alleviates vacuolization and necrosis in tubular epithelial cells induced by aortic cross-clamping.

S Ergene, D Hemsinli, SO Karakisi… - European Review for …, 2023 - 79.123.160.167
OBJECTIVE: Acute kidney injury (AKI) is one of the main causes of mortality in patients
undergoing emergency surgery due to an abdominal aortic aneurysm. This study aimed to …