Atrial septal defect in adulthood: a new paradigm for congenital heart disease

M Brida, M Chessa, D Celermajer, W Li… - European Heart …, 2022 - academic.oup.com
Atrial septal defects (ASDs) represent the most common congenital heart defect diagnosed
in adulthood. Although considered a simple defect, challenges in optimal diagnostic and …

[HTML][HTML] Challenges and opportunities of integrating imaging and mathematical modelling to interrogate biological processes

M Berg, N Holroyd, C Walsh, H West… - … International Journal of …, 2022 - Elsevier
Advances in biological imaging have accelerated our understanding of human physiology in
both health and disease. As these advances have developed, the opportunities gained by …

A mock circulation loop to characterize in vitro hemodynamics in human systemic arteries with stenosis

W Hong, H Yu, J Chen, J Talamantes, DM Rollins… - Fluids, 2023 - mdpi.com
Vascular disease is the leading cause of morbidity and mortality and a major cause of
disability for Americans, and arterial stenosis is its most common form in systemic arteries …

Formulation of a nonlocal discrete model for anisotropic heat conduction problems

H Chen, D Liu - International Journal of Thermal Sciences, 2022 - Elsevier
In this paper, we present the formulation of a nonlocal discrete model based on a lattice
particle method for modeling anisotropic heat conduction problems. In the proposed model …

Thoroughly calibrated modular agent-based model of the human cardiovascular and renal systems for blood pressure regulation in health and disease

E Kutumova, I Kiselev, R Sharipov, G Lifshits… - Frontiers in …, 2021 - frontiersin.org
Here we present a modular agent-based mathematical model of the human cardiovascular
and renal systems. It integrates the previous models primarily developed by AC Guyton, F …

A method of parameter estimation for cardiovascular hemodynamics based on deep learning and its application to personalize a reduced‐order model

Y Zhou, Y He, J Wu, C Cui, M Chen… - International Journal for …, 2022 - Wiley Online Library
Precise model personalization is a key step towards the application of cardiovascular
physical models. In this manuscript, we propose to use deep learning (DL) to solve the …

[HTML][HTML] Perlin noise generation of physiologically realistic cardiac fibrosis

BAJ Lawson, C Drovandi, P Burrage… - Medical Image …, 2024 - Elsevier
Fibrosis, a pathological increase in extracellular matrix proteins, is a significant health issue
that hinders the function of many organs in the body, in some cases fatally. In the heart …

Optimizing group work strategies in virtual dissection

L Evans, L Singer, D Zahra, I Agbeja… - Anatomical Sciences …, 2024 - Wiley Online Library
Due to its haptic and interactive nature, virtual anatomy provides an opportunity for small‐
group learning, enabling students to develop their group work skills before they graduate …

[HTML][HTML] A Review of Personalised Cardiac Computational Modelling Using Electroanatomical Mapping Data

OA Jaffery, L Melki, G Slabaugh, WW Good… - Arrhythmia & …, 2024 - ncbi.nlm.nih.gov
Computational models of cardiac electrophysiology have gradually matured during the past
few decades and are now being personalised to provide patient-specific therapy guidance …

From fetus to neonate: A review of cardiovascular modeling in early life

RW May, GD Maso Talou, AR Clark… - WIREs Mechanisms …, 2023 - Wiley Online Library
Computational modeling has well‐established utility in the study of cardiovascular
hemodynamics, with applications in medical research and, increasingly, in clinical settings …