The role of diffusion tensor imaging in idiopathic normal pressure hydrocephalus: A literature review

I Grazzini, D Venezia… - The neuroradiology …, 2021 - journals.sagepub.com
Idiopathic normal pressure hydrocephalus (iNPH) is a syndrome that comprises a triad of
gait disturbance, dementia and urinary incontinence, associated with ventriculomegaly in …

The novel imaging methods in diagnosis and assessment of cerebrovascular diseases: an overview

F Liu, Y Yao, B Zhu, Y Yu, R Ren, Y Hu - Frontiers in Medicine, 2024 - frontiersin.org
Cerebrovascular diseases, including ischemic strokes, hemorrhagic strokes, and vascular
malformations, are major causes of morbidity and mortality worldwide. The advancements in …

The impact of multimorbidity burden, frailty risk scoring, and 3-directional morphological indices vs. testing for CSF responsiveness in normal pressure hydrocephalus

SXY Soon, AA Kumar, AJL Tan, YT Lo, C Lock… - Frontiers in …, 2021 - frontiersin.org
Objective: Multimorbidity burden across disease cohorts and variations in clinico-
radiographic presentations within normal pressure hydrocephalus (NPH) confound its …

Neuroimaging data repositories and AI-driven healthcare—Global aspirations vs. ethical considerations in machine learning models of neurological disease

C Lock, NSM Tan, IJ Long, NC Keong - Frontiers in Artificial …, 2024 - frontiersin.org
Neuroimaging data repositories are data-rich resources comprising brain imaging with
clinical and biomarker data. The potential for such repositories to transform healthcare is …

Mining multi-site clinical data to develop machine learning MRI biomarkers: application to neonatal hypoxic ischemic encephalopathy

RJ Weiss, SV Bates, Y Song, Y Zhang… - Journal of translational …, 2019 - Springer
Background Secondary and retrospective use of hospital-hosted clinical data provides a
time-and cost-efficient alternative to prospective clinical trials for biomarker development …

The splenial angle: a novel radiological index for idiopathic normal pressure hydrocephalus

LL Chan, R Chen, H Li, AJY Lee, WY Go, W Lee… - European …, 2021 - Springer
Objectives To evaluate the utility of the splenial angle (SA), an axial angular index of lateral
ventriculomegaly measured on diffusion tensor MRI color fractional anisotropy maps, in …

Structural volumetric and Periodic Table DTI patterns in Complex Normal Pressure Hydrocephalus—Toward the principles of a translational taxonomy

C Lock, EMS Toh, NC Keong - Frontiers in Human Neuroscience, 2024 - frontiersin.org
Introduction We previously proposed a novel taxonomic framework to describe the diffusion
tensor imaging (DTI) profiles of white matter tracts by their diffusivity and neural properties …

Diffusion tensor imaging profiles can distinguish diffusivity and neural properties of white matter injury in hydrocephalus vs. non-hydrocephalus using a strategy of a …

NC Keong, C Lock, S Soon, AT Hernowo… - Frontiers in …, 2022 - frontiersin.org
Background: The aim of this study was to create a simplistic taxonomy to improve
transparency and consistency in, and reduce complexity of, interpreting diffusion tensor …

Callosal angle in idiopathic normal pressure hydrocephalus: Small angular mal-rotations of the coronal plane affect measurement reliability

W Lee, A Lee, H Li, NYX Ong, N Keong, R Chen… - Neuroradiology, 2021 - Springer
Purpose The callosal angle (CA) is a useful biomarker in the diagnosis and management of
idiopathic normal pressure hydrocephalus (NPH). Used incorrectly, CA measurements are …

Modeling the properties of white matter tracts using diffusion tensor imaging to characterize patterns of injury in aging and neurodegenerative disease

CY Kok, C Lock, TY Ang, NC Keong - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
Diffusion tensor imaging (DTI) is a relatively novel magnetic resonance-based imaging
methodology that can provide valuable insight into the microstructure of white matter tracts of …