Chemotherapy is still the first line of treatment for most cancer patients. Patients receiving
chemotherapy are generally prone to infections, which result in complications, such as …

The chemical investigation of marine mollusks has led to the isolation of a wide variety of
bioactive metabolites, which evolved in marine organisms as favorable adaptations to …

The past several decades have seen a paradigm shift with the integration of evolutionary
thinking into studying cancer. The evolutionary lens is most commonly employed in …

Dogs are remarkable, adaptable, and dependable creatures that have evolved alongside
humans while contributing tremendously to our survival. Our canine companions share …

Comparative oncology is defined as the discipline that integrates naturally occurring cancers
seen in veterinary medicine, into more general studies of cancer biology and therapy in …

Preclinical studies in rodent models have been a pivotal role in human clinical research, but
many of them fail in the translational process. Spontaneous tumors in pet dogs have the …

Purpose TRAF4 plays an important role in the development and progression of breast
cancer, but its impact on chemotherapy resistance is as yet, however, poorly understood …

Pet dogs with naturally occurring cancers play an important role in studies of cancer biology
and drug development. We assessed tolerability, efficacy, and pharmacokinetic …

The present study aimed to design and synthesize a series of phenyl-isoxazole-
carboxamide derivatives and investigate their antitumor and antioxidant activities. The in …

Swine biomedical models have been gaining in popularity over the last decade, particularly
for applications in oncology research. Swine models for cancer research include pigs that …