The anatomy of the mammalian visual system, from the retina to the neocortex, is organized
hierarchically. However, direct observation of cellular-level functional interactions across this …

The mechanisms underlying neuronal coding and, in particular, the role of temporal spike
coordination are hotly debated. However, this debate is often confounded by an implicit …

The existence and role of fine-temporal structure in the spiking activity of central neurons is
the subject of an enduring debate among physiologists. To a large extent, the problem is a …

Brain function relies on the coordination of activity across multiple, recurrently connected
brain areas. For instance, sensory information encoded in early sensory areas is relayed to …

The spiking activity of cortical neurons is correlated. For instance, trial-to-trial fluctuations in
response strength are shared between neurons, and spikes often occur synchronously …

Seizures are classically characterized as the expression of hypersynchronous neural
activity, yet the true degree of synchrony in neuronal spiking (action potentials) during …

The mammalian visual system, from retina to neocortex, has been extensively studied at
both anatomical and functional levels. Anatomy indicates the cortico-thalamic system is …

The brain is composed of billions of neurons, the elementary units of neuronal information
processing. The neocortex, which is critical to most higher brain functions, is a highly …

Background During active (or REM) sleep, infant mammals exhibit myoclonic twitches of
skeletal muscles throughout the body, generating jerky, discrete movements of the distal …

On the timescale of sensory processing, neuronal networks have relatively fixed anatomical
connectivity, while functional interactions between neurons can vary depending on the …