A new methodology has been developed for the synthesis of highly substituted nitrogen
heterocycles such as pyrazines and imidazoles starting from α-diketones using phosphine …

We report a short synthetic route for synthesizing 2, 3-substituted piperazine acetic acid
esters. Optically pure amino acids were efficiently converted into 1, 2-diamines that could be …

The synthesis of pyrazines is described using a sequence that begins with the diazidation of
N-allyl malonamides followed by thermal or copper-mediated cyclization. The pyrazine …

A facile transformation of amino acids into substituted 1, 4-dihydropyridines (1, 4-DHP) is
reported. The natural amino acids were converted into gamma-amino beta-keto esters and …

Neste trabalho foi desenvolvida uma rota sintética simples e eficiente para a síntese de 2H-
azirinas contendo um grupo metileno ativado. As 2H-azirinas foram preparadas a partir dos …