Huntington disease (HD) is an autosomal dominant neurodegenerative disease that is
caused by expansion of cytosine/adenosine/guanine repeats in the huntingtin (HTT) gene …

Circadian clock mechanisms are far-from-equilibrium dissipative structures. Peroxisome
proliferator-activated receptors (PPAR alpha, beta/delta, and gamma) play a key role in …

Sympathetic neurons densely innervate the myocardium with non‐random topology and
establish structured contacts (ie neuro‐cardiac junctions, NCJ) with cardiomyocytes …

Cardiac remodelling and contractile dysfunction occur during both acute and chronic
disease processes including the accumulation of insoluble aggregates of misfolded amyloid …

Amyloid-like inclusions have been associated with Huntington's disease (HD), which is
caused by expanded polyglutamine repeats in the Huntingtin protein. HD patients exhibit a …

Abstract Background Although Huntington's disease (HD) is usually thought of as a triad of
motor, cognitive, and psychiatric symptoms, there is growing appreciation of HD as a …

Although Huntington's disease is generally considered to be a neurological disorder, there
is mounting evidence that heart malfunction plays an important role in disease progression …

Huntington's disease (HD) is a neurodegenerative disorder caused by a toxic, aggregation-
prone expansion of CAG repeats in the HTT gene with an age-dependent progression that …

Huntington's disease (HD) is a multi-system disorder that is caused by expanded CAG
repeats within the exon-1 of the huntingtin (HTT) gene that translate to the polyglutamine …

Huntington's disease (HD) is a rare neurodegenerative disease that is accompanied by
skeletal muscle atrophy and cardiomyopathy. Tissues affected by HD (central nervous …