Cooperative catalysis and activation with N‐heterocyclic carbenes

MH Wang, KA Scheidt - Angewandte Chemie International …, 2016 - Wiley Online Library
N‐Heterocyclic carbene (NHC) catalysis has emerged as a powerful stratagem in organic
synthesis to construct complex molecules primarily by polarity reversal (umpolung) …

N‐heterocyclic carbene/copper cooperative catalysis for the asymmetric synthesis of spirooxindoles

ZJ Zhang, L Zhang, RL Geng, J Song… - Angewandte …, 2019 - Wiley Online Library
Abstract Highly enantioselective [3+ 3] and [3+ 4] annulations of isatin‐derived enals with
ethynylethylene carbonates and ethynyl benzoxazinanones are enabled by NHC/cooper …

Palladium-catalyzed multicomponent reactions: an overview

S Saranya, KR Rohit, S Radhika… - Organic & Biomolecular …, 2019 - pubs.rsc.org
This first review on this topic focuses on the developments in the chemistry of Pd-catalyzed
multi-component reactions (MCRs). MCRs are generally atom economic, ideal and eco …

Cooperative Lewis acid/N-heterocyclic carbene catalysis

DT Cohen, KA Scheidt - Chemical science, 2012 - pubs.rsc.org
Lewis acid activation with N-heterocyclic carbene (NHC) catalysis has presented new
opportunities for enantioselective reaction development. Recent findings illustrate that Lewis …

N-Heterocyclic Carbene and Brønsted Acid Cooperative Catalysis: Asymmetric Synthesis of trans-γ-Lactams

X Zhao, DA DiRocco, T Rovis - Journal of the American Chemical …, 2011 - ACS Publications
An efficient enantioselective approach to form trans-γ-lactams in up to 99% yield, 93% ee,
and> 20/1 dr using unactivated imines has been developed. The cyclohexyl-substituted …

[HTML][HTML] Lewis acid activated synthesis of highly substituted cyclopentanes by the N-heterocyclic carbene catalyzed addition of homoenolate equivalents to …

DT Cohen, B Cardinal-David… - … Chemie (International ed …, 2011 - ncbi.nlm.nih.gov
The stereoselective construction of highly functionalized small-and medium-sized
carbocycles from simple substrates is an ongoing objective in organic synthesis. One …

A Family of Thiazolium Salt Derived N‐Heterocyclic Carbenes (NHCs) for Organocatalysis: Synthesis, Investigation and Application in Cross‐Benzoin Condensation

I Piel, MD Pawelczyk, K Hirano, R Fröhlich, F Glorius - 2011 - Wiley Online Library
A family of thiazolium salt derived N‐heterocyclic carbenes (NHCs) bearing sterically
demanding aryl substituents on the nitrogen and with varying backbone substitution patterns …

Kooperative Katalyse mit N‐heterocyclischen Carbenen

MH Wang, KA Scheidt - Angewandte Chemie, 2016 - Wiley Online Library
Die Katalyse mit N‐heterocyclischen Carbenen (NHC) hat sich in der organischen Synthese
zu einer leistungsfähigen Strategie entwickelt, um komplexe Moleküle hauptsächlich durch …

NHC/Iron cooperative catalysis: aerobic oxidative esterification of aldehydes with phenols

RS Reddy, JN Rosa, LF Veiros, S Caddick… - Organic & Biomolecular …, 2011 - pubs.rsc.org
NHC/Iron cooperative catalysis: aerobic oxidative esterification of aldehydes with phenols -
Organic & Biomolecular Chemistry (RSC Publishing) DOI:10.1039/C1OB05151B Royal …

Synergistic N‐Heterocyclic Carbene/Palladium‐Catalyzed Reactions of Aldehyde Acyl Anions with either Diarylmethyl or Allylic Carbonates

S Yasuda, T Ishii, S Takemoto… - Angewandte Chemie …, 2018 - Wiley Online Library
Benzylation and allylation of aldehyde acyl anions were enabled by the merger of a
thiazolium N‐heterocyclic carbene (NHC) catalyst and a palladium/bisphosphine catalyst in …