Stroke and the neurovascular unit: glial cells, sex differences, and hypertension

HW Morrison, JA Filosa - American Journal of Physiology …, 2019 - journals.physiology.org
A functional neurovascular unit (NVU) is central to meeting the brain's dynamic metabolic
needs. Poststroke damage to the NVU within the ipsilateral hemisphere ranges from cell …

Orchidectomy attenuates high‐salt diet‐induced increases in blood pressure, renovascular resistance, and hind limb vascular dysfunction: role of testosterone

AK Oloyo, OA Sofola, MA Yakubu - Clinical and Experimental …, 2016 - Wiley Online Library
Sex hormone‐dependent vascular reactivity is an underlying factor contributing to sex
differences in salt‐dependent hypertension. This study evaluated the role of androgens …

L-arginine supplementation lowers blood pressure, protein excretion and plasma lipid profile in experimental salt-induced hypertension in pregnancy: Relevance to …

AP Arikawe, IC Udenze, AW Olusanya… - Pathophysiology, 2019 - Elsevier
This study aimed to investigate the effects of L-arginine supplementation on blood pressure,
protein excretion, lipid profile in salt-induced hypertensive pregnant rats. Female Sprague …

Antioxidant and apoptosis-inhibition potential of Carpobrotus edulis in a model of parkinson's disease

AB Enogieru, SI Omoruyi, OE Ekpo - Journal of African Association of …, 2018 - ajol.info
Background: Parkinson's disease (PD) is a neurological disorder resulting from the
progressive loss of dopaminergic neurons. There is currently no known cure for PD, thus the …

l-arginine Supplementation Increased Only Endothelium-Dependent Relaxation in Sprague-Dawley Rats Fed a High-Salt Diet by Enhancing Abdominal Aorta …

A Adejare, A Oloyo, C Anigbogu… - Clinical Medicine …, 2020 - journals.sagepub.com
Background: Abnormal vascular reactivity and reduced expression of endothelial nitric oxide
synthase (eNOS) gene are hallmark of salt-induced hypertension in rats. Although l-arginine …

Testosterone promotes glucose intolerance, lipid disorder and oxidative stress in type 1 diabetic rats

AO Morakinyo, DA Adekunbi, KA Dada… - Journal of Basic and …, 2014 - degruyter.com
Background: A bidirectional relationship has been established between testosterone
deficiency (TD) and type 2 diabetes mellitus (T2DM). Low testosterone level has been …

Sex differences in cardiac and renal responses to a high salt diet in Sprague-Dawley rats

AK Oloyo, NOA Imaga, Y Fatope, OA Sofola - Heliyon, 2019 - cell.com
High dietary salt intake is an important risk factor for cardiovascular and renal diseases.
However, sexual disparity exists in the response of target organs to high salt diet (HSD). To …

[HTML][HTML] Renal denervation ameliorated salt-induced hypertension by improving cardiac work, cardiac enzyme and oxidative balance in Sprague-Dawley rats

A Adejare, A Oloyo, Y Dahud, M Adeshina… - International Journal of …, 2024 - Elsevier
Background Hypertension is associated with cardiovascular dysfunction, dysregulation of
the antioxidant system and alteration of the level of some enzymes in the metabolic pathway …

Testosterone reduces vascular relaxation by altering cyclic adenosine monophosphate pathway and potassium channel activation in male Sprague Dawley rats fed a …

AK Oloyo, OA Sofola, CN Anigbogu… - Therapeutic …, 2013 - journals.sagepub.com
Objectives: Male gender and high-salt diet are risk factors for hypertension. The effect of
chronic exposure to testosterone is an increase in vascular tone but its influence upon …

Adverse effect of graded Ciprofloxacin oral intake in male Sprague-Dawley rats

YD Igbayilola, WA Saka, SO Aina… - Journal of African …, 2020 - ajol.info
Background: Ciprofloxacin (CF) is a very popular antibiotics used for therapeutic prospects.
This study was investigated to determine the effect of graded CF oral intake on lipid profile …