In-depth structural characterization of lipids is an essential component of lipidomics. There
has been a rapid expansion of mass spectrometry methods that are capable of resolving …

MS/MS currently serves as the workhorse for metabolomics. Structural identification is
extremely important to correlate statistical variables to biochemical functions and …

A lipidome comprises thousands of lipid species, many of which are isomers and isobars.
Liquid chromatography-tandem mass spectrometry (LC-MS/MS), although widely used for …

Lipids are highly diverse biomolecules associated with several biological functions including
structural constituent, energy storage, and signal transduction. It is essential to characterize …

Reported here is the first on‐demand electrochemical epoxidation incorporated into the
standard nano‐electrospray ionization mass spectrometry (nanoESI‐MS) workflow for …

Single-cell analysis is critical to revealing cell-to-cell heterogeneity that would otherwise be
lost in ensemble analysis. Detailed lipidome characterization for single cells is still far from …

Cellular lipidome is highly regulated through lipogenesis, rendering diverse double-bond
positional isomers (C═ C isomer) of a given unsaturated lipid species. In recent years, there …

Monounsaturated fatty acids are straight-chain aliphatic monocarboxylic acids comprising a
unique carbon‑carbon double bond, also termed unsaturation. More than 50 distinct …

Conspectus Lipids have pivotal roles in many biological processes, including energy
storage, signal transduction, and plasma membrane formation. A disruption of lipid …

Mass spectrometry imaging (MSI) of lipids in biological tissues is useful for correlating
molecular distribution with pathological results, which could provide useful information for …