MDMA-assisted therapy for moderate to severe PTSD: a randomized, placebo-controlled phase 3 trial

JM Mitchell, M Ot'alora G, B van der Kolk, S Shannon… - Nature Medicine, 2023 - nature.com
This multi-site, randomized, double-blind, confirmatory phase 3 study evaluated the efficacy
and safety of 3, 4-methylenedioxymethamphetamine-assisted therapy (MDMA-AT) versus …

Written exposure therapy vs prolonged exposure therapy in the treatment of posttraumatic stress disorder: A randomized clinical trial

DM Sloan, BP Marx, R Acierno, M Messina… - JAMA …, 2023 - jamanetwork.com
Importance Evidence-based treatments for posttraumatic stress disorder (PTSD) exist, but all
require 8 to 15 sessions and thus are less likely to be completed than brief treatments …

Exposure therapy for PTSD in military populations: A systematic review and meta-analysis of randomized clinical trials

CP McLean, HC Levy, ML Miller, DF Tolin - Journal of anxiety disorders, 2022 - Elsevier
Military populations are disproportionally affected by posttraumatic stress disorder (PTSD)
and may experience less benefit from first line psychotherapies for PTSD relative to civilians …

Is it worth it to personalize the treatment of PTSD?–A variance-ratio meta-analysis and estimation of treatment effect heterogeneity in RCTs of PTSD

P Herzog, T Kaiser - Journal of Anxiety Disorders, 2022 - Elsevier
Several evidence-based treatments for posttraumatic stress disorder (PTSD) are
recommended by international guidelines (eg, APA, NICE). While their average effects are in …

Why some psychotherapists benefit from feedback on treatment progress more than others: A belief updating perspective.

P Herzog, T Kube, J Rubel - Clinical Psychology: Science and …, 2023 - psycnet.apa.org
Monitoring of patient-reported outcomes and providing therapists with progress feedback
has been shown to be beneficial for treatment outcomes (eg, by preventing therapy failures) …

[HTML][HTML] Effects of MDMA-assisted therapy for PTSD on self-experience

BA van der Kolk, JB Wang, R Yehuda, L Bedrosian… - PLoS …, 2024 - journals.plos.org
Introduction There is a resurgence of interest in the therapeutic potential of psychedelic
substances such as 3, 4-methylenedioxymethamphetamine (MDMA). Primary findings from …

The role of therapy delivery and clinic organizational factors in explaining therapist effects for trauma-focused psychotherapies in the Veterans Health Administration.

NA Sayer, S Wiltsey Stirman, CS Rosen… - Journal of consulting …, 2023 - psycnet.apa.org
Objective: This study estimated the size of therapist effects (TEs) for dropout and clinical
effectiveness of two trauma-focused psychotherapies (TFPs) and evaluated whether therapy …

Yoga vs cognitive processing therapy for military sexual trauma–related posttraumatic stress disorder: A randomized clinical trial

B Zaccari, M Higgins, TN Haywood, M Patel… - JAMA Network …, 2023 - jamanetwork.com
Importance First-line treatment for posttraumatic stress disorder (PTSD) in the US
Department of Veterans Affairs (VA), ie, trauma-focused therapy, while effective, is limited by …

A randomized trial of brief couple therapy for PTSD and relationship satisfaction.

LA Morland, KC Knopp, CE Khalifian… - Journal of Consulting …, 2022 - psycnet.apa.org
Objective: This three-arm randomized trial tested a brief version of cognitive-behavioral
conjoint therapy (bCBCT) delivered in two modalities compared to couples' …

The potential of ketamine for posttraumatic stress disorder: a review of clinical evidence

A Ragnhildstveit, J Roscoe, LC Bass… - Therapeutic …, 2023 - journals.sagepub.com
Posttraumatic stress disorder (PTSD) is a devastating condition, for which there are few
pharmacological agents, often with a delayed onset of action and poor efficacy. Trauma …