Sickle cell disease (SCD) is a widespread disease caused by a mutation in the beta-globin
gene that leads to the production of abnormal hemoglobin called hemoglobin S. The …

Human red blood cells (RBCs) are approximately 8 μm in diameter, but must repeatedly
deform through capillaries as small as 2 μm in order to deliver oxygen to all parts of the …

Microfluidic impedance cytometry is a label-free technique for high-throughput single-cell
analysis. Multi-frequency impedance measurements provide data that allows full …

Biophysical cellular information at single-cell sensitivity is becoming increasingly important
within analytical and separation platforms that associate the cell phenotype with markers of …

This study is aim to investigate the dielectric properties (dielectric constant, ε′ and loss
factor, ε′′) and the biodegradation properties of the nano-hydroxyapatite/starch bone …

A laboratory blood test is vital for assessing a patient's health and disease status. Advances
in microfluidic technology have opened the door for on-chip blood analysis. Currently …

Objective: Deformability is an essential feature of red blood cells (RBCs), enabling them to
undergo significant shape change in response to external forces. Impaired erythrocyte …

Sickle cell disease (SCD) is a worldwide hematological disorder causing painful episodes,
anemia, organ damage, stroke, and even deaths. It is more common in sub-Saharan Africa …

Hypoxia‐induced polymerization of sickle hemoglobin and the related ion diffusion across
cell membrane can lead to changes in cell dielectric properties, which can potentially serve …

In this work, we demonstrate a multifunctional, portable, and disposable microfluidic device
for blood typing and primary screening of blood diseases. Preloaded antibodies (anti-A, anti …