The dual role of the glycosaminoglycan chondroitin‐6‐sulfate in the development, progression and metastasis of cancer

A Pudełko, G Wisowski, K Olczyk… - The FEBS Journal, 2019 - Wiley Online Library
The remarkable structural heterogeneity of chondroitin sulfate (CS) and dermatan sulfate
(DS) generates biological information that can be unique to each of these …

Chondroitin: a natural biomarker with immense biomedical applications

D Pal, S Saha - RSC advances, 2019 - pubs.rsc.org
Naturally extracted glycosaminoglycan chondroitin sulphate is the reactive product of N-
acetylgalactosamine and D-glucuronic acid. Chondroitin sulfate (CS) extracted from …

Nano-elemental selenium particle developed via supramolecular self-assembly of chondroitin sulfate A and Na2SeO3 to repair cartilage lesions

J Han, H Deng, Y Li, L Qiao, H Jia, L Zhang… - Carbohydrate …, 2023 - Elsevier
Cartilage repair is a significant clinical issue due to its restricted ability to regenerate and self-
heal after cartilage lesions or degenerative disease. Herein, a nano-elemental selenium …

Serious selenium deficiency in the serum of patients with Kashin–Beck disease and the effect of nano-selenium on their chondrocytes

L Wang, J Yin, B Yang, C Qu, J Lei, J Han… - Biological trace element …, 2020 - Springer
To investigate selenium (Se) concentrations in serum of patients with rheumatoid arthritis
(RA), osteoarthritis (OA), and Kashin–Beck disease (KBD), together with the effect of Se …

Genomics and transcriptomics reveal new molecular mechanism of vibriosis resistance in fish

Q Zhou, Y Chen, Z Chen, L Wang, X Ma… - Frontiers in …, 2022 - frontiersin.org
Infectious diseases have caused dramatic production decline and economic loss for fish
aquaculture. However, the poor understanding of fish disease resistance severely …

Arthritis and Duchenne muscular dystrophy: The role of chondroitin sulfate and its associated proteoglycans in disease pathology and as a diagnostic marker

ML Maciej-Hulme, J Melrose… - American Journal of …, 2023 - journals.physiology.org
Chondroitin sulfate (CS) is a ubiquitous glycosaminoglycan covalently attached to the core
proteins of cell surface, extracellular, and intracellular proteoglycans. The multistep and …

Sulfation pattern of chondroitin sulfate in human osteoarthritis cartilages reveals a lower level of chondroitin-4-sulfate

TS Lin, CH Hsieh, C Kuo, YP Juang, YSY Hsieh… - Carbohydrate …, 2020 - Elsevier
Chondroitin sulfates (CS) account for more than 80% of the glycosaminoglycans of articular
cartilage, which impart its physiological functions. We quantified the absolute concentration …

Proteomic analysis of knee cartilage reveals potential signaling pathways in pathological mechanism of Kashin-Beck disease compared with osteoarthritis

J Lei, AF Amhare, L Wang, Y Lv, H Deng, H Gao… - Scientific Reports, 2020 - nature.com
The pathological mechanism of Kashin-Beck disease (KBD), an endemic osteoarthritic
disease, remains to be poorly understood. This study was designed to identify signaling …

Knockdown of carbohydrate sulfotransferase 12 decreases the proliferation and mobility of glioblastoma cells via the WNT/β-catenin pathway

J Wang, X Xia, X Tao, P Zhao, C Deng - Bioengineered, 2021 - Taylor & Francis
Glioblastoma (GBM) is a common malignant tumor of the brain. Members of the
carbohydrate sulfotransferase (CHST) family are deregulated in various cancer types …

[HTML][HTML] Proteomics analysis of hip articular cartilage identifies differentially expressed proteins associated with osteonecrosis of the femoral head

J Song, J Wu, B Poulet, J Liang, C Bai, X Dang… - Osteoarthritis and …, 2021 - Elsevier
Objective The cartilage degeneration that accompanies subchondral bone necrosis plays an
important role in the development of osteonecrosis of femoral head (ONFH). To better …