Novel structural hybrids of quinoline and thiazole moieties: Synthesis and evaluation of antibacterial and antifungal activities with molecular modeling studies

SI Eissa, AM Farrag, SY Abbas, MF El Shehry… - Bioorganic …, 2021 - Elsevier
One of the best ways to design new biocidal agents is synthesizing hybrid molecules by
combining two or more bioactive moieties in a single molecular scaffold. So, new series of …

Synthesis, antimicrobial and cytotoxic activities of some novel thiazole clubbed 1, 3, 4-oxadiazoles

NC Desai, N Bhatt, H Somani, A Trivedi - European Journal of Medicinal …, 2013 - Elsevier
A series of thiazole clubbed 1, 3, 4-oxadiazole derivatives (5a–l) have been synthesized and
characterized by IR, 1 H NMR, 13 C NMR and mass spectral analysis. Synthesized …

Synthesis of some new 2-(3-pyridyl)-4, 5-disubstituted thiazoles as potent antimicrobial agents

S Bondock, T Naser, YA Ammar - European Journal of Medicinal Chemistry, 2013 - Elsevier
As a part of ongoing studies in developing new potent antimicrobial agents, a series of novel
2-(3-pyridyl)-4, 5-disubstituted thiazoles was efficiently synthesized and characterized by …

Facile synthesis of novel fluorine containing pyrazole based thiazole derivatives and evaluation of antimicrobial activity

NC Desai, VV Joshi, KM Rajpara, HV Vaghani… - Journal of Fluorine …, 2012 - Elsevier
A series of compounds 2-(5-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)-3-(aryl)-4, 5-
dihydro-1H-pyrazol-1-yl) thiazol-4 (5H)-ones (4a–q) were synthesized and structures of …

[HTML][HTML] Penicillin-Resistant trend of Streptococcus pneumoniae in Asia: A systematic review

S Mamishi, S Moradkhani, S Mahmoudi… - Iranian journal of …, 2014 - ncbi.nlm.nih.gov
The high prevalence of resistance to penicillin by Streptococcus pneumoniaeis considered
as a great concern, particularly in Asian countries. The aim of this study was to investigate …

Comparison of efficacy of azithromycin vs. doxycycline in the treatment of acne vulgaris

S Kus, D Yucelten, A Aytug - Clinical and experimental …, 2005 - academic.oup.com
Acne vulgaris is a common inflammatory disorder of the skin. Oral antibiotics are known to
be effective in its treatment. A randomized, investigator‐blinded study was performed to …

Synthesis and in vitro study of methylene-bis-tetrahydro [1, 3] thiazolo [4, 5-c] isoxazoles as potential nematicidal agents

A Srinivas, A Nagaraj, CS Reddy - European journal of medicinal chemistry, 2010 - Elsevier
A series of methylene-bis-tetrahydro [1, 3] thiazolo [4, 5-c] isoxazoles 6 were synthesized by
the reaction of chalcone derivative of methylene-bis-thiazolidinone 5 with hydroxylamine …

Antibiotic Resistance in Pathogenic Streptococcus pneumoniaeIsolates in Turkey

H Erdem, A Pahsa - Journal of chemotherapy, 2005 - Taylor & Francis
Streptococcus pneumoniae causes various human infections such as meningitis,
septicemia, otitis media, sinusitis, and pneumonia. Antibiotic resistance has already been …

Synthesis and Antioxidant Activity of 2‐Amino‐5‐methylthiazol Derivatives Containing 1, 3, 4‐Oxadiazole‐2‐thiol Moiety

KN Mohana, CBP Kumar - International Scholarly Research …, 2013 - Wiley Online Library
A series of new 5‐(2‐amino‐5‐methylthiazol‐4‐yl)‐1, 3, 4‐oxadiazole‐2‐thiol derivatives 6
(a–j) were designed and synthesized with various substituted aldehydes. The chemical …

[HTML][HTML] Synthesis and study of 1, 3, 5-triazine based thiazole derivatives as antimicrobial agents

NC Desai, AH Makwana, KM Rajpara - Journal of Saudi Chemical Society, 2016 - Elsevier
A series of novel compounds N′-(4-(arylamino)-6-(thiazol-2-ylamino)-1, 3, 5-triazin-2-yl)
isonicotinohydrazides (3a− l) were synthesized by a series of multistep reactions. Newly …