[HTML][HTML] Advances of microfluidic lung chips for assessing atmospheric pollutants exposure

H Wang, F Yin, Z Li, W Su, D Li - Environment International, 2023 - Elsevier
Atmospheric pollutants, including particulate matters, nanoparticles, bioaerosols, and some
chemicals, have posed serious threats to the environment and the human's health. The …

Scaling up complexity in synthetic developmental biology

G Martínez-Ara, KS Stapornwongkul, M Ebisuya - Science, 2022 - science.org
The application of synthetic biology approaches to study development opens the possibility
to build and manipulate developmental processes to understand them better. Researchers …

The promise and potential of brain organoids

L Smirnova, T Hartung - Advanced Healthcare Materials, 2024 - Wiley Online Library
Brain organoids are 3D in vitro culture systems derived from human pluripotent stem cells
that self‐organize to model features of the (developing) human brain. This review examines …

Synthetic developmental biology: molecular tools to re-design plant shoots and roots

EG Kocaoglan, D Radhakrishnan… - Journal of …, 2023 - academic.oup.com
Plant morphology and anatomy strongly influence agricultural yield. Crop domestication has
strived for desirable growth and developmental traits, such as larger and more fruits and …

Plant synthetic biology: exploring the frontiers of sustainable agriculture and fundamental plant biology

JS Yang, I Reyna-Llorens - Journal of Experimental Botany, 2023 - academic.oup.com
Plant synthetic biology allows for the reprogramming of biological systems to promote
sustainable agriculture. It has a range of applications, including improving nutritional quality …

[HTML][HTML] Generative models of morphogenesis in developmental biology

NR Stillman, R Mayor - Seminars in Cell & Developmental Biology, 2023 - Elsevier
Understanding the mechanism by which cells coordinate their differentiation and migration
is critical to our understanding of many fundamental processes such as wound healing …

Synthetic symmetry breaking and programmable multicellular structure formation

N Wauford, A Patel, J Tordoff, C Enghuus, A Jin… - Cell Systems, 2023 - cell.com
During development, cells undergo symmetry breaking into differentiated subpopulations
that self-organize into complex structures. 1, 2, 3, 4, 5 However, few tools exist to …

Application of colloidal photonic crystals in study of organoids

K Huang, Q Li, Y Xue, Q Wang, Z Chen, Z Gu - Advanced Drug Delivery …, 2023 - Elsevier
As alternative disease models, other than 2D cell lines and patient-derived xenografts,
organoids have preferable in vivo physiological relevance. However, both endogenous and …

Control of spatio-temporal patterning via cell growth in a multicellular synthetic gene circuit

M Santorelli, PS Bhamidipati, J Courte… - Nature …, 2024 - nature.com
A major goal in synthetic development is to build gene regulatory circuits that control
patterning. In natural development, an interplay between mechanical and chemical …

Automatic design of gene regulatory mechanisms for spatial pattern formation

R Mousavi, D Lobo - npj Systems Biology and Applications, 2024 - nature.com
Gene regulatory mechanisms (GRMs) control the formation of spatial and temporal
expression patterns that can serve as regulatory signals for the development of complex …