Chalcones (1, 3-diaryl-2-propen-1-ones) are precursors for flavonoids and isoflavonoids,
which are common simple chemical scaffolds found in many naturally occurring compounds …

The need for innovative anticancer treatments with high effectiveness and low toxicity is
urgent due to the development of malignancies that are resistant to chemotherapeutic …

In recent years, the interest in flavonoids as dietary bioactives to prevent human diseases,
as well as their candidacy as pharmaceutical leads, has exponentially expanded …

Chalcones are intermediate products in the biosynthesis of flavonoids, which possess a
wide range of biological properties, including antimicrobial and anticancer activities. The …

Chalcones are interesting anticancer drug candidates which have attracted much interest
due to their unique structure and their extensive biological activity. Various functional …

The great possibility of synthetic modifications available in different aspects has elevated
porphyrins as an appealing candidate for a plethora of applications. Accordingly, changes in …

In the literature, only two papers describe the synthesis of 3-mercaptocoumarins (3-MCMs)
without exploring their bioactivity. So, the novelty of this work is driven by the fact that it …

The aim of the study was to compare the impact of three synthesized chemical compounds
from a group of methylated flavonoids, ie 2′-hydroxy-4-methylchalcone (3), 4 …

Chalcones are members of the flavonoid family and act as intermediates in the biosynthesis
of flavonoids, which are widespread in plants. Meanwhile, chalcones are important …

Fluorene was previously reported to have anticancer activity against human cancer cells. In
this study, we examined the in vitro function of 9-methanesulfonylmethylene-2, 3-dimethoxy …