Cell alignment plays a critical role in various cell behaviors including cytoskeleton
reorganization, membrane protein relocation, nucleus gene expression, and ECM …

Mechanical loads induce changes in the structure, composition, and function of living
tissues. Cells in tissues are responsible for these changes, which cause physiological or …

Although the need for a functional arterial replacement is clear, the lower blood flow
velocities of small-diameter arteries like the coronary artery have led to the failure of …

Organs and tissues adapt to acute or chronic mechanical stress by remodeling their actin
cytoskeletons. Cells that are stimulated by cyclic stretch or shear stress in vitro undergo …

Vascular endothelial cells (ECs) play a central role in the control of blood vessel function
and circulatory system homeostasis. It is well known that that EC functions are regulated by …

Several epidemiological studies have reported that an elevated heart rate is associated with
coronary atherosclerosis independently of other risk factors. In this review we explore the …

Cutaneous wound healing is a complex process with many types of mechanical forces
regulating the quality and speed of healing. The role of mechanical forces in regulating …

Although vascular bypass grafting remains the mainstay for revascularization for ischemic
heart disease and peripheral vascular disease, many patients do not have healthy vessels …

Risk assessment in patients with carotid atherosclerosis relies on the degree of luminal
stenosis. Incorporating morphological information on plaque composition obtained …

Vascular endothelium is a potential target for therapeutic intervention in diverse pathological
processes, including inflammation, atherosclerosis, and thrombosis. By virtue of their …