Biology of endophilin and it's role in disease

LQ Yang, AF Huang, WD Xu - Frontiers in Immunology, 2023 - frontiersin.org
Endophilin is an evolutionarily conserved family of protein that involves in a range of
intracellular membrane dynamics. This family consists of five isoforms, which are distributed …

The impact of transmembrane peptides on lipid bilayer structure and mechanics: A study of the transmembrane domain of the influenza A virus M2 protein

YI Gamage, Y Wadumesthri, HR Gutiérrez… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Transmembrane peptides play important roles in many biological processes by interacting
with lipid membranes. This study investigates how the transmembrane domain of the …

[HTML][HTML] Membrane activity and viroporin assembly for the SARS-CoV-2 E protein are regulated by cholesterol

MV Volovik, ZG Denieva, PK Gifer, MA Rakitina… - Biomolecules, 2024 - mdpi.com
The SARS-CoV-2 E protein is an enigmatic viral structural protein with reported viroporin
activity associated with the acute respiratory symptoms of COVID-19, as well as the ability to …

[HTML][HTML] Lipid species dependent vesicles clustering caused by alpha-synuclein as revealed by single-vesicle imaging with total internal reflection fluorescence …

CM Aryal, O Tyoe, J Diao - Biophysics reports, 2021 - ncbi.nlm.nih.gov
Lipid species dependent vesicles clustering caused by alpha-synuclein as revealed by
single-vesicle imaging with total internal reflection fluorescence microscopy - PMC Back to Top …

[HTML][HTML] The N-terminal helices of amphiphysin and endophilin have different capabilities of membrane remodeling

CM Aryal, NN Bui, L Song, J Pan - Biochimica et Biophysica Acta (BBA) …, 2022 - Elsevier
Amphiphysin and endophilin are two members of the N-BAR protein family. We have
reported membrane interactions of the helix 0 of endophilin (H0-Endo). Here we investigate …

Docosahexaenoic acid promotes vesicle clustering mediated by alpha-Synuclein via electrostatic interaction

O Tyoe, C Aryal, J Diao - The European Physical Journal E, 2023 - Springer
Abstract α-Synuclein (α-Syn) is an intrinsically disordered protein whose aggregation is
associated with Parkinson's disease, dementia, and other neurodegenerative diseases …

Elucidating the Influence of Lipid Composition on Bilayer Perturbations Induced by the N-terminal Region of the Huntingtin Protein

YI Gamage, J Pan - Biophysica, 2023 - mdpi.com
Understanding the membrane interactions of the N-terminal 17 residues of the huntingtin
protein (HttN) is essential for unraveling its role in cellular processes and its impact on …

Probing the interactions of the HIV-1 matrix protein-derived polybasic region with lipid bilayers: insights from AFM imaging and force spectroscopy

CM Aryal, J Pan - European Biophysics Journal, 2024 - Springer
The human immunodeficiency virus type 1 (HIV-1) matrix protein contains a highly basic
region, MA-HBR, crucial for various stages of viral replication. To elucidate the interactions …

Peripheral membrane protein endophilin B1 probes, perturbs and permeabilizes lipid bilayers

A Thorlacius, M Rulev, O Sundberg, A Sundborger - bioRxiv, 2024 - biorxiv.org
Bin/Amphiphysin/Rvs (BAR) domain containing proteins are cytosolic, peripheral membrane
proteins that regulate the curvature of membranes in eukaryotic cells. BAR protein …

Peripheral membrane protein endophilin B1 probes, perturbs and permeabilizes lipid bilayers

A Sundborger-Lunna, A Thorlacius, M Rulev… - 2024 - researchsquare.com
Abstract Bin/Amphiphysin/Rvs (BAR) domain containing proteins are cytosolic, peripheral
membrane proteins that regulate the curvature of membranes in eukaryotic cells. BAR …