Three-and four-membered rings, widespread motifs in nature and medicinal chemistry, have
fascinated chemists ever since their discovery. However, due to energetic considerations …

For centuries, gold had been considered a precious, purely decorative inert metal. It was not
until 1986 that Ito and Hayashi described the first application of gold (I) in homogeneous …

Homogeneous gold-catalyzed cyclopropanation has emerged as a powerful method in
organic synthesis due to its rich chemistry and fascinating reactivity. This thriving strategy is …

N-Heterocyclic carbenes (NHCs) are cyclic carbenes bearing at least one R-amino
substituent. 1 The most common subclasses of NHCs are represented in Chart 1. Early work …

Gold salts and complexes have emerged in the past few years as the most powerful
catalysts for electrophilic activation of alkynes toward a variety of nucleophiles under …

Substituted heterocycles are a structural component of a vast number of biologically active
natural and non-natural compounds. Synthesis of various heterocycles has been a research …

Cationic gold complexes in which gold is bound to a formally divalent carbon atom, typically
formulated as gold carbenes or α-metallocarbenium ions, have been widely invoked in a …

The appealing properties of N-heterocyclic carbenes (NHC) as ancillary ligands and the
high potential of gold as an organometallic catalyst have made their encounter inevitable …

The strong σ-donor but poor π-acceptor abilities of N-heterocyclic carbenes (NHCs) result in
chemical stability and coordination versatility, thus allowing them to coordinate with many …

Gold (I)-catalyzed addition of carbon nucleophiles to 1, 6-enynes gives two different type of
products by reaction at the cyclopropane or at the carbene carbons of the intermediate …