KP Kepp - Chemical reviews, 2012 - ACS Publications
Alzheimer's disease (AD) 1− 3 is the most common form of dementia (estimated∼ 50− 60% of all cases), associated with loss of memory (in particular episodic memory), cognitive …
Background There is an expanding field of research investigating the benefits of medicines with multiple mechanisms of action across neurological disorders. N‐acetylcysteine (NAC) …
DA Butterfield, MP Mattson - Neurobiology of disease, 2020 - Elsevier
Inheritance of apolipoprotein E4 (APOE4) is a major risk factor for development of Alzheimer's disease (AD). This lipoprotein, in contrast to apoE2, has arginine residues at …
R Obeid, W Herrmann - FEBS letters, 2006 - Elsevier
Mild to moderate hyperhomocysteinemia is a risk factor for neurodegenerative diseases. Human studies suggest that homocysteine (Hcy) plays a role in brain damage, cognitive and …
TS Anekonda - Brain research reviews, 2006 - Elsevier
Resveratrol, a red wine polyphenol, is known to protect against cardiovascular diseases and cancers, as well as to promote antiaging effects in numerous organisms. It also modulates …
D Luque-Contreras, K Carvajal… - Oxidative medicine …, 2014 - Wiley Online Library
Alzheimer's disease (AD) is a major neurodegenerative disease affecting the elderly. Clinically, it is characterized by a progressive loss of memory and cognitive function …
M Okouchi, O Ekshyyan, M Maracine… - Antioxidants & redox …, 2007 - liebertpub.com
Apoptosis mediates the precise and programmed natural death of neurons and is a physiologically important process in neurogenesis during maturation of the central nervous …
M Arakawa, Y Ito - The Cerebellum, 2007 - Springer
Increasing lines of evidence suggest a key role of oxidative stress in neurodegenerative diseases. Alzheimer's disease, Parkinson's disease, myoclonus epilepsy of the Unverricht …
A Fuso, V Nicolia, RA Cavallaro, L Ricceri… - Molecular and cellular …, 2008 - Elsevier
Etiological and molecular studies on the sporadic form of Alzheimer's disease have yet to determine the underlying mechanisms of neurodegeneration. Hyperhomocysteinemia is …