The kidney is a crucial organ that eliminates metabolic waste and reabsorbs nutritious
elements. It also participates in the regulation of blood pressure, maintenance of electrolyte …

The anti-aging effects of alpha-lipoic acid (αLA), a natural antioxidant synthesized in human
tissues, have attracted a growing interest in recent years. αLA is a short-chain sulfur …

The research determined the role of α‐lipoic acid (ALA) in reducing the brain manifestations
of insulin resistance. The mechanism of ALA action is mainly based on its ability to …

In recent years, it has been identified that excess iron contributes to the development of
various pathologies and their complications. Kidney diseases do not escape the toxic effects …

Smoking has been associated with NAFLD recently, thus might be a contributing factor for
liver disease progression. In this study, we identified the modulative action of α‐lipoic acid (α …

Background Oxidative stress underlies metabolic diseases and cognitive impairment; thus,
the use of antioxidants may improve brain function in insulin-resistant conditions. We are the …

Kidney diseases have rapidly increased in prevalence over the past few decades, and have
now become a major global public health concern. This has put economic burden on the …

OBJECTIVES: The purpose of this study is to investigate the effects of cholinergic anti-infl
ammatory pathway (CAP)-activating drugs, choline and citicoline (Cytidinediphosphate …

Ischemia-reperfusion injury is related to kidney dysfunction due to bilateral lower limb
ischemia. This kidney injury may lead to acute kidney failure and mortality. Alpha-Lipoic …

Background: A growing body of evidence indicates the regulating effects of alpha-lipoic acid
on iron metabolism. However, findings from clinical trials are equivocal. This systematic …