Endometriosis is defined as the presence of endometrial-like glands and stroma located
outside the uterine cavity. This common, estrogen dependent, inflammatory condition affects …

A healthy immune system is pivotal for the hosts to resist external pathogens and maintain
homeostasis; however, the immunosuppressive tumor microenvironment (TME) damages …

This study focused on the effects of Bifidobacterium breve CCFM1078 on the intestinal
barrier and systemic inflammation of collagen-induced arthritis (CIA) rats. Female rats were …

Immune thrombocytopenia is a common heterogeneous autoimmune disease that is
characterized by decreasing peripheral blood platelet counts and increasing risk of …

The Th17+ arrangement is critical for orchestrating both innate and acquired immune
responses. In this context, the serum and glucocorticoid regulated kinase 1 (SGK1) exerts a …

Abstract γ-Tocotrienol (GT3), a member of the vitamin E family, is well known for its
medicinal value in clinical treatments. However, the role of GT3 in T helper 17 …

The effects of specific cytokines produced by T cell subsets (such as Th1, Th2, and newly
discovered Th17, Treg, Tfh, or Th22) are diverse, depending on interactions with other …

Background Chronic HBV infection is always accompanied by differences in the balance
between regulatory T cells (Tregs) and T-helper 17 (Th17) cells in infection phases. IL-21 …

Introduction Ubiquitin-specific proteases (USPs), a large subset of more than 50
deubiquitinase proteins, have recently emerged as promising targets in cancer. However …

Osteosarcoma (OS) is a heterogeneous malignant spindle cell tumor that is aggressive and
has a poor prognosis. Although combining surgery and chemotherapy has significantly …