Alzheimer disease is a progressive neurodegenerative disorder, mainly affecting older
people, which severely impairs patients' quality of life. In the recent years, the number of …

Autophagy is an evolutionarily conserved lysosome-or vacuole-dependent catabolic
pathway in eukaryotes. Autophagy functions basally for cellular quality control and is …

Atherosclerosis-associated cardiovascular disease is one of the main causes of death and
disability among patients with diabetes mellitus. However, little is known about the impact of …

Background Down syndrome (DS) individuals, by the age of 40s, are at increased risk to
develop Alzheimer-like dementia, with deposition in brain of senile plaques and …

Fatty acids (FAs) are critical nutrients that regulate an organism's health and development in
mammal. Long-chain fatty acids (LCFAs) can be divided into saturated and unsaturated fatty …

Despite the great increase in human lifespan with improved medical care, the physiological
and pathological changes such as memory and cognitive disorders and associated anxiety …

The accumulation of adenosine in the tumor microenvironment is associated with tumor
progression in many cancers. However, whether adenosine is involved in gastric cancer …

Unrelenting cognitive and mood impairments concomitant with incessant oxidative stress
and neuroinflammation are among the significant symptoms of chronic Gulf War Illness …

Spinal cord injury (SCI) is a serious refractory disease of the central nervous system (CNS),
which mostly caused by high-energy trauma. Existing interventions such as hormone shock …

Neuronal survival depends on the glia, that is, on the astroglial and microglial support.
Neurons die and microglia are activated not only in neurodegenerative diseases but also in …