DNA sequencing at 40: past, present and future
This review commemorates the 40th anniversary of DNA sequencing, a period in which we
have already witnessed multiple technological revolutions and a growth in scale from a few …
have already witnessed multiple technological revolutions and a growth in scale from a few …
International Union of Basic and Clinical Pharmacology. CX. Classification of receptors for 5-hydroxytryptamine; pharmacology and function
5-HT receptors expressed throughout the human body are targets for established
therapeutics and various drugs in development. Their diversity of structure and function …
therapeutics and various drugs in development. Their diversity of structure and function …
The environmental influences on child health outcomes (ECHO)-wide cohort
EA Knapp, AM Kress, CB Parker… - American journal of …, 2023 - academic.oup.com
Abstract The Environmental Influences on Child Health Outcomes (ECHO)-Wide Cohort
Study (EWC), a collaborative research design comprising 69 cohorts in 31 consortia, was …
Study (EWC), a collaborative research design comprising 69 cohorts in 31 consortia, was …
Finding the genomic basis of local adaptation: pitfalls, practical solutions, and future directions
Uncovering the genetic and evolutionary basis of local adaptation is a major focus of
evolutionary biology. The recent development of cost-effective methods for obtaining high …
evolutionary biology. The recent development of cost-effective methods for obtaining high …
Genotyping-by-sequencing (GBS), an ultimate marker-assisted selection (MAS) tool to accelerate plant breeding
J He, X Zhao, A Laroche, ZX Lu, HK Liu… - Frontiers in plant …, 2014 - frontiersin.org
Marker-assisted selection (MAS) refers to the use of molecular markers to assist phenotypic
selections in crop improvement. Several types of molecular markers, such as single …
selections in crop improvement. Several types of molecular markers, such as single …
Chemistry, biology, and medicine of fluorescent nanomaterials and related systems: new insights into biosensing, bioimaging, genomics, diagnostics, and therapy
J Yao, M Yang, Y Duan - Chemical reviews, 2014 - ACS Publications
2. INTRODUCTION The investigation of many fundamental processes in life sciences
requires straightforward tools for fast, sensitive, reliable, and reproducible detection of …
requires straightforward tools for fast, sensitive, reliable, and reproducible detection of …
SNP markers and their impact on plant breeding
J Mammadov, R Aggarwal… - … journal of plant …, 2012 - Wiley Online Library
The use of molecular markers has revolutionized the pace and precision of plant genetic
analysis which in turn facilitated the implementation of molecular breeding of crops. The last …
analysis which in turn facilitated the implementation of molecular breeding of crops. The last …
Target-enrichment strategies for next-generation sequencing
L Mamanova, AJ Coffey, CE Scott, I Kozarewa… - Nature …, 2010 - nature.com
We have not yet reached a point at which routine sequencing of large numbers of whole
eukaryotic genomes is feasible, and so it is often necessary to select genomic regions of …
eukaryotic genomes is feasible, and so it is often necessary to select genomic regions of …
Applications of next-generation sequencing to phylogeography and phylogenetics
This is a time of unprecedented transition in DNA sequencing technologies. Next-generation
sequencing (NGS) clearly holds promise for fast and cost-effective generation of multilocus …
sequencing (NGS) clearly holds promise for fast and cost-effective generation of multilocus …
The sequence of the human genome
A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human
genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion …
genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion …