Synthetic polymers are omnipresent in society as textiles and packaging materials, in
construction and medicine, among many other important applications. Alternatively, natural …

This article describes the state of the art in the field of antimicrobial polymeric systems during
the last decade. Keeping in mind the multitude of existing systems, a classification of the …

The increasing prevalence of antibiotic-resistant bacterial infections, coupled with the
decline in the number of new antibiotic drug approvals, has created a therapeutic gap that …

Macromolecular antimicrobial agents such as cationic polymers and peptides have recently
been under an increased level of scrutiny because they can combat multi-drug-resistant …

Membrane-disruptive peptides/peptidomimetics (MDPs) are antimicrobials or
anticarcinogens that present a general killing mechanism through the physical disruption of …

Antimicrobial peptides (AMPs) provide protection against a variety of pathogenic bacteria
and are, therefore, an important part of the innate immune system. Over the past decade …

Foldamers are sequence-specific oligomers akin to peptides, proteins and oligonucleotides
that fold into well-defined three-dimensional structures. They offer the chemical biologist a …

Synthetic macromolecular antimicrobials are a highly promising class of therapeutics with
immense potential for combating multidrug resistant microbes. In contrast to conventional …

Osteomyelitis is a major complication of orthopedic diseases with high recurrence and
morbidity, along with long hospital stays and high medical costs. The conventional treatment …

This critical review covers progress with synthetic transport systems, particularly ion
channels and pores, between January 2006 and December 2009 in a comprehensive …