Interaction between the microbiota, epithelia, and immune cells in the intestine

H Kayama, R Okumura, K Takeda - Annual review of …, 2020 - annualreviews.org
The gastrointestinal tract harbors numerous commensal bacteria, referred to as the
microbiota, that benefit host health by digesting dietary components and eliminating …

[HTML][HTML] Butyrate: a double-edged sword for health?

H Liu, J Wang, T He, S Becker, G Zhang, D Li, X Ma - Advances in nutrition, 2018 - Elsevier
Butyrate, a four-carbon short-chain fatty acid, is produced through microbial fermentation of
dietary fibers in the lower intestinal tract. Endogenous butyrate production, delivery, and …

Biological function of short-chain fatty acids and its regulation on intestinal health of poultry

L Liu, Q Li, Y Yang, A Guo - Frontiers in Veterinary Science, 2021 - frontiersin.org
Short-chain fatty acids (SCFAs) are metabolites generated by bacterial fermentation of
dietary fiber (DF) in the hindgut. SCFAs are mainly composed of acetate, propionate and …

Immune regulation by microbiome metabolites

CH Kim - Immunology, 2018 - Wiley Online Library
Commensal microbes and the host immune system have been co‐evolved for mutual
regulation. Microbes regulate the host immune system, in part, by producing metabolites. A …

Role of short-chain fatty acids in colonic inflammation, carcinogenesis, and mucosal protection and healing

CM van der Beek, CHC Dejong, FJ Troost… - Nutrition …, 2017 - academic.oup.com
Short-chain fatty acids (SCFAs), mainly acetate, propionate, and butyrate, produced by
microbial fermentation of undigested food substances are believed to play a beneficial role …

Commensal bacteria at the interface of host metabolism and the immune system

JR Brestoff, D Artis - Nature immunology, 2013 - nature.com
The mammalian gastrointestinal tract, the site of digestion and nutrient absorption, harbors
trillions of beneficial commensal microbes from all three domains of life. Commensal …

[HTML][HTML] Understanding the holobiont: how microbial metabolites affect human health and shape the immune system

TS Postler, S Ghosh - Cell metabolism, 2017 - cell.com
The human gastrointestinal tract is populated by a diverse, highly mutualistic microbial flora,
which is known as the microbiome. Disruptions to the microbiome have been shown to be …

Role of the gut microbiota in human nutrition and metabolism

BS Ramakrishna - Journal of gastroenterology and hepatology, 2013 - Wiley Online Library
The human gastrointestinal tract harbors trillions of bacteria, most of which are commensal
and have adapted over time to the milieu of the human colon. Their many metabolic …

From the gut to the peripheral tissues: the multiple effects of butyrate

P Guilloteau, L Martin, V Eeckhaut… - Nutrition research …, 2010 - cambridge.org
Butyrate is a natural substance present in biological liquids and tissues. The present paper
aims to give an update on the biological role of butyrate in mammals, when it is naturally …

The role of butyrate on colonic function

HM Hamer, D Jonkers, K Venema… - Alimentary …, 2008 - Wiley Online Library
Background Butyrate, a short‐chain fatty acid, is a main end‐product of intestinal microbial
fermentation of mainly dietary fibre. Butyrate is an important energy source for intestinal …