Various nutritional, behavioral, and pharmacological interventions have been previously
shown to extend life span in diverse model organisms, including Saccharomyces cerevisiae …

Recent evidence suggests that calorie restriction and specifically reduced glucose
metabolism induces mitochondrial metabolism to extend life span in various model …

Increasing evidence indicates that reactive oxygen species (ROS), consisting of superoxide,
hydrogen peroxide, and multiple others, do not only cause oxidative stress, but rather may …

Mitochondria are organized in the cell in the form of a dynamic, interconnected network.
Mitochondrial dynamics, regulated by mitochondrial fission, fusion, and trafficking, ensure …

Impaired insulin and IGF-1 signaling (iIIS) in C. elegans daf-2 mutants extends life span
more than 2-fold. Constitutively, iIIS increases mitochondrial activity and reduces reactive …

Aging is characterized by a progressive loss of muscle mass and muscle strength. Declines
in skeletal muscle mitochondria are thought to play a primary role in this process …

The Free Radical/Oxidative Stress Theory of Aging, which was first proposed in 1956, is
currently one of the most popular explanations for how aging occurs at the …

The free radical hypothesis of aging proposes that deleterious actions of oxygen-derived
radicals are responsible for the functional deterioration associated with aging. Because …

Oxidative stress is observed during aging and in numerous age-related diseases. Dietary
restriction (DR) is a regimen that protects against disease and extends life span in multiple …

This study was designed to demonstrate the effects of 900-MHz electromagnetic field (EMF)
emitted from cellular phone on brain tissue and also blood malondialdehyde (MDA) …