The development of more specific biomarkers for prostate cancer and/or high‐risk prostate
cancer is necessary, because the prostate‐specific antigen test lacks specificity for the …

Simple Summary Apart from genetic changes, cancer is characterized by epigenetic
alterations, which indicate modifications in the DNA (such as DNA methylation) and histones …

Simple Summary Liquid biopsy (LB), encompassing the analysis of circulating tumor
material in the blood or urine, has emerged as a powerful tool in the management of …

HOX genes are commonly known for their role in embryonic development, defining the
positional identity of most structures along the anterior–posterior axis. In postembryonic life …

Differentially methylated CpG sites (dmCpGs) that distinguish prostate tumour from adjacent
benign tissue could aid in the diagnosis and prognosis of prostate cancer. Previously, the …

The coding region of GSTP1 gene is preceded by a large CpG-rich region that is frequently
affected by methylation. In many cancer types, GSTP1 is affected by hypermethylation and …

Simple Summary Prostate cancer (PCa) is the most frequent malignancy, and the second
leading cause of cancer-related death, in men in the United States. PCa detection has been …

Background Biliary tract cancers (BTC) are rare but highly aggressive tumours with poor
prognosis, usually detected at advanced stages. Herein, we aimed at identifying BTC …

Prostate cancer (CaP) is the most common cancer in men and the second leading cause of
cancer deaths in males in Australia. Although serum prostate-specific antigen (PSA) has …

Background Significant numbers of prostate cancer (PCa) patients experience tumour
upstaging and upgrading in surgical specimens that cause serious problems in timely and …