Clustered regularly interspaced short palindromic repeat/crispr-associated protein and its utility all at sea: status, challenges, and prospects

J Li, S Wu, K Zhang, X Sun, W Lin, C Wang, S Lin - Microorganisms, 2024 - mdpi.com
Initially discovered over 35 years ago in the bacterium Escherichia coli as a defense system
against invasion of viral (or other exogenous) DNA into the genome, CRISPR/Cas has …

Genome Editing Using the CRISPR-Cas9 System to Generate a Solid-Red Germline of Nile Tilapia (Oreochromis niloticus)

A Segev-Hadar, T Slosman, A Rozen… - The CRISPR …, 2021 - liebertpub.com
In recent years, there has been increasing demand for red tilapia, which are commercial
strains of hybrids of different tilapiine species or red variants of highly inbred Nile tilapia …

The freshwater water flea Daphnia magna NIES strain genome as a resource for CRISPR/Cas9 gene targeting: the glutathione S-transferase omega 2 gene

E Byeon, MS Kim, DH Kim, Y Lee, H Jeong, JS Lee… - Aquatic Toxicology, 2022 - Elsevier
The water flea Daphnia magna is a small freshwater planktonic animal in the Cladocera. In
this study, we assembled the genome of the D. magna NIES strain, which is widely used for …

Generation of golden goldfish Carassius auratus via tyrosinase gene targeting by CRISPR/Cas9

H Li, X Wang, R Zhang, L Liu, H Zhu - Aquaculture, 2024 - Elsevier
Gene editing technology based on CRISPR/cas9 system has a pivotal application prospect
in promoting the genetic improvement of economic traits of aquaculture animals, and has …

Effects of lipophilic phycotoxin okadaic acid on the early development and transcriptional expression of marine medaka Oryzias melastigma

Y Yang, A Li, J Qiu, W Yan, L Han, D Li, C Yin - Aquatic Toxicology, 2023 - Elsevier
The lipophilic okadaic acid (OA)-group toxins produced by some species of Dinophysis spp.
and Prorocentrum spp. marine dinoflagellates have been frequently and widely detected in …

Generation of Albino Phenotype in Ornamental Fish by CRISPR/Cas9-Mediated Genome Editing of slc45a2 Gene

C Zhang, Z Ren, Z Gong - Marine Biotechnology, 2023 - Springer
Albinism is the most common color variation described in fish and is a fascinating trait of
some ornamental fish species. Albino mutants can be generated by knocking out core genes …

Identification of Potential Blind-Side Hypermelanosis-Related lncRNA–miRNA–mRNA Regulatory Network in a Flatfish Species, Chinese Tongue Sole (Cynoglossus …

Y Li, Y Hu, P Cheng, S Chen - Frontiers in Genetics, 2022 - frontiersin.org
Blind-side hypermelanosis has emerged as a major concern in commercial rearing
environments of the flatfish aquaculture industry. To date, the underlying molecular …

Easy-to-Use CRISPR-Cas9 Genome Editing in the Cultured Pacific Abalone (Haliotis discus hannai)

R Li, Y Xu, F Wu, Z Peng, J Chan, L Zhang - The CRISPR Journal, 2024 - liebertpub.com
The Pacific abalone is an important aquaculture shellfish and serves as an important model
in basic biology study. However, the study of abalone is limited by lack of highly efficient and …

[HTML][HTML] Dynamic changes in pigmentation-related gene expression during morphogenesis in Plectropomus leopardus revealed by comparative transcriptome …

X Liu, H Zhang, K Zhang, X Deng, C He, H Chen, G Li… - Aquaculture, 2025 - Elsevier
Plectropomus leopardus is a valuable marine aquaculture fish, prized by consumers for its
high nutritional value and gorgeous appearance. The economic significance of this species …

Two High-Quality Cygnus Genome Assemblies Reveal Genomic Variations Associated with Plumage Color

Y Chong, X Tu, Y Lu, Z Gao, X He, J Hong… - International Journal of …, 2023 - mdpi.com
As an exemplary model for examining molecular mechanisms responsible for extreme
phenotypic variations, plumage color has garnered significant interest. The Cygnus genus …