Emerging potential of 5-Fluorouracil-loaded chitosan nanoparticles in cancer therapy

TT Dongsar, TS Dongsar, N Gupta, WH Almalki… - Journal of Drug Delivery …, 2023 - Elsevier
Cancer is among the leading causes of mortality in the globe. Chemotherapy utilizing
various anticancer medicines continues to be the most widely used form of treatment …

Advances in mucoadhesion and mucoadhesive polymers

VV Khutoryanskiy - Macromolecular bioscience, 2011 - Wiley Online Library
Mucoadhesion is the ability of materials to adhere to mucosal membranes in the human
body and provide a temporary retention. This property has been widely used to develop …

The basics and underlying mechanisms of mucoadhesion

JD Smart - Advanced drug delivery reviews, 2005 - Elsevier
Mucoadhesion is where two surfaces, one of which is a mucous membrane, adhere to each
other. This has been of interest in the pharmaceutical sciences in order to enhance localised …

Mucoadhesive polymeric platforms for controlled drug delivery

GP Andrews, TP Laverty, DS Jones - European journal of pharmaceutics …, 2009 - Elsevier
The process of mucoadhesion involving a polymeric drug delivery platform is a complex one
that includes wetting, adsorption and interpenetration of polymer chains amongst various …

Buccal bioadhesive drug delivery—a promising option for orally less efficient drugs

Y Sudhakar, K Kuotsu, AK Bandyopadhyay - Journal of controlled release, 2006 - Elsevier
Rapid developments in the field of molecular biology and gene technology resulted in
generation of many macromolecular drugs including peptides, proteins, polysaccharides …

Buparvaquone mucoadhesive nanosuspension: preparation, optimisation and long-term stability

RH Müller, C Jacobs - International journal of pharmaceutics, 2002 - Elsevier
The poorly soluble drug buparvaquone is used in experimental clinics against the
gastrointestinal persisting parasite Cryptosporidium parvum. It was produced as …

Swelling behavior of acrylic acid hydrogels prepared by γ-radiation crosslinking of polyacrylic acid in aqueous solution

E Jabbari, S Nozari - European Polymer Journal, 2000 - Elsevier
Swelling behavior of anionic acrylic acid polyelectrolyte hydrogel synthesized by γ-radiation
crosslinking of polyacrylic acid in aqueous solution was investigated. Cross-linked …

Mucoadhesion and mechanical assessment of oral films

S Alaei, H Omidian - European Journal of Pharmaceutical Sciences, 2021 - Elsevier
Aligned with efforts to overcome shortcomings of conventional oral dosage forms,
mucoadhesive oral thin films have been the focus of drug development. Transmucosal drug …

A rheological examination of the mucoadhesive/mucus interaction: the effect of mucoadhesive type and concentration

F Madsen, K Eberth, JD Smart - Journal of controlled release, 1998 - Elsevier
The ability of mucoadhesive polymers to produce a large increase in the resistance to
deformation when incorporated into a mucus gel, relative to when the mucus gel and test …

Bioadhesion of hydrated chitosans: an in vitro and in vivo study

I Henriksen, KL Green, JD Smart, G Smistad… - International journal of …, 1996 - Elsevier
The (bio) adhesivity of several chitosan chloride samples was screened in vitro and
compared with hydroxypropyl-methylcellulose (HPMC), Carbopol 934P and polycarbophil …