Hepatotoxicity is among the most frequent reasons for drug withdrawal from the market.
Therefore, there is an urgent need for reliable predictive in vitro tests, which unfailingly …

The human placenta and umbilical cord, natural birth biowaste, are a housing unit for
numerous bioactive macromolecules, growth factors, collagen and GAGs, with an array of …

Hepatitis delta virus (HDV), a satellite virus of HBV, is regarded as the most severe type of
hepatitis virus because of the substantial morbidity and mortality. The IFN system is the first …

Laminins are extracellular matrix proteins that reside in the basement membrane and
provide structural support in addition to promoting cellular adhesion and migration. Through …

The safety and short-term efficacy of hepatocyte transplantation (HCTx) have been widely
proven. However, issues such as reduced viability and/or function of hepatocytes …

Although hepatocyte transplantation and bioartificial liver support system provide new
promising opportunities for those patients waiting for liver transplantation, hepatocytes are …

Abstract Human Amniotic Epithelial Cells (hAEC) isolated from term placenta are a
promising source for regenerative medicine. However, it has long been debated whether the …

Use of hepatocytes derived from induced pluripotent stem cells (i-Heps) is limited by their
functional differences in comparison with primary cells. Extracellular niche factors likely play …

Currently, one of the most serious public health issues is the increasing number of cases of
chronic liver disease and cirrhosis both of which can lead to liver failure. The only effective …

Orthotopic liver transplantation is presently the most effectual method for the treatment of
end‐stage liver diseases. Though, one major issue is the restricted number of donor organs …