Neuroimaging-based brain age estimation: A promising personalized biomarker in neuropsychiatry

D Sone, I Beheshti - Journal of Personalized Medicine, 2022 - mdpi.com
It is now possible to estimate an individual's brain age via brain scans and machine-learning
models. This validated technique has opened up new avenues for addressing clinical …

Integrating Clinical Neuropsychology and Psychotic Spectrum Disorders: A Systematic Analysis of Cognitive Dynamics, Interventions, and Underlying Mechanisms

E Gkintoni, M Skokou, P Gourzis - Medicina, 2024 - mdpi.com
Background and Objectives: The study aims to provide a comprehensive
neuropsychological analysis of psychotic spectrum disorders, including schizophrenia …

Predicting aging trajectories of decline in brain volume, cortical thickness and fractional anisotropy in schizophrenia

JD Zhu, SJ Tsai, CP Lin, YJ Lee, AC Yang - Schizophrenia, 2023 - nature.com
Brain-age prediction is a novel approach to assessing deviated brain aging trajectories in
different diseases. However, most studies have used an average brain age gap (BAG) of …

Brain Age Gap as a Predictor of Early Treatment Response and Functional Outcomes in First-Episode Schizophrenia: A Longitudinal Study: L'écart d'âge cérébral …

L Fan, Z Zhang, X Ma, L Liang, L Yuan… - The Canadian …, 2024 - journals.sagepub.com
Résumé Objectifs Le vieillissement accéléré du cerveau, c'est-à-dire les modifications
structurelles du cerveau liées à l'âge et apparaissant plus tôt que prévu par rapport à l'âge …

Potential of brain age in identifying early cognitive impairment in subcortical small-vessel disease patients

Y Shi, H Mao, Q Gao, G Xi, S Zeng, L Ma… - Frontiers in Aging …, 2022 - frontiersin.org
Background Reliable and individualized biomarkers are crucial for identifying early cognitive
impairment in subcortical small-vessel disease (SSVD) patients. Personalized brain age …

Deep learning-based brain age prediction in patients with schizophrenia spectrum disorders

WS Kim, DW Heo, J Maeng, J Shen… - Schizophrenia …, 2024 - academic.oup.com
Abstract Background and Hypothesis The brain-predicted age difference (brain-PAD) may
serve as a biomarker for neurodegeneration. We investigated the brain-PAD in patients with …

[HTML][HTML] Association between visual impairment and psychosis: A longitudinal study and nested case-control study of adults

N Shoham, G Lewis, JF Hayes, SM Silverstein… - Schizophrenia …, 2023 - Elsevier
Background Theories propose that visual impairment might increase the risk of psychosis,
and vice versa. We aimed to investigate the relationship between visual impairment and …

Sex-difference in the association between social drinking, structural brain aging and cognitive function in older individuals free of cognitive impairment

OA Abulseoud, EC Caparelli, J Krell‐Roesch… - Frontiers in …, 2024 - frontiersin.org
Background We investigated a potential sex difference in the relationship between alcohol
consumption, brain age gap and cognitive function in older adults without cognitive …

[HTML][HTML] Assessing the association between global structural brain age and polygenic risk for schizophrenia in early adulthood: A recall-by-genotype study

C Constantinides, V Baltramonaityte, D Caramaschi… - cortex, 2024 - Elsevier
Neuroimaging studies consistently show advanced brain age in schizophrenia, suggesting
that brain structure is often 'older'than expected at a given chronological age. Whether …

Temporal changes of gene expression in health, schizophrenia, bipolar disorder, and major depressive disorder

A Arakelyan, S Avagyan, A Kurnosov, T Mkrtchyan… - Schizophrenia, 2024 - nature.com
The molecular events underlying the development, manifestation, and course of
schizophrenia, bipolar disorder, and major depressive disorder span from embryonic life to …